Carbene transformations have had an enormous impact on catalysis and organometallic chemistry. With the growth of transition metal-catalyzed carbene transformations in recent decades, carbene transformations are today an important compound class in organic synthesis as well as in the pharmaceutical and agrochemical industries. Edited by leading experts in the field, Transition Metal-Catalyzed Carbene Transformations is a thorough summary of the most recent advances in the rapidly expanding research area.

This authoritative volume covers different reaction types such as ring forming reactions and rearrangement reactions, details their conditions and properties, and provides readers with accurate information on a wide range of carbene reactions. Twelve in-depth chapters address topics including carbene C-H bond insertion in alkane functionalization, the application of engineered enzymes in asymmetric carbene transfer, progress in transition-metal-catalyzed cross-coupling using carbene precursors, and more. Throughout the text, the authors highlight novel catalytic systems, transformations, and applications of transition-metal-catalyzed carbene transfer.

• Highlights the dynamic nature of the field of transition-metal-catalyzed carbene transformations
• Summarizes the catalytic radical approach for selective carbene cyclopropanation, high enantioselectivity in X-H insertions, and bio-inspired carbene transformations
• Introduces chiral N,N'-dioxide and chiral guanidine-based catalysts and different transformations with gold catalysis
• Discusses approaches in cycloaddition reactions with metal carbenes and polymerization with carbene transformations
• Outlines multicomponent reactions through gem-difunctionalization and transition-metal-catalyzed cross-coupling using carbene precursors

Transition Metal-Catalyzed Carbene Transformations is essential reading for all chemists involved in organometallics, including organic and inorganic chemists, catalytic chemists, and chemists working in industry.

Jianbo Wang is Full Professor at Peking University, China. He has published more than 300 articles in peer-reviewed journals and serves as Associate Editor of Journal of Physical Organic Chemistry and Chinese Journal of Organic Chemistry.

Chi-Ming Che is Dr. Hui Wai-Haan Chair of Chemistry at The University of Hong Kong (HKU) and Director of China's State Key Laboratory of Synthetic Chemistry. His honors include the China State Natural Science Award and the Centenary Prize from the Royal Society of Chemistry.

Michael P. Doyle is Rita and John Feik Distinguished University Chair in Medicinal Chemistry at The University of Texas, San Antonio, TX, USA. He has received numerous awards and is the author and co-author of numerous books and more than 400 journal publications.