Biological Modulation of Solid Tumours by Interferons

Biological Modulation of Solid Tumours by Interferons

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In the 1960s, it was reported that interferons have antitumour activity in different experimental models. Since that time, numerous studies have been performed to elucidate the various mechanisms of action that have been proposed. However, there is much controversy in the literature and promising preclinical findings failed to translate into substantial clinical progress. The present book gives a critical overview of current knowledge of how interferons act in solid tumours. For this purpose, after two chapters of general aspects of interferon action and interaction, selected solid tumours which are commonly considered difficult to treat in advanced stages are discussed with respect to both preclinical data and clinical experience.

The Interferons: Basic Concepts Concerning their Modulatory Effects on the Immunological System
Biomodulation of 5-Fluorouracil by Interferon-Alpha
Malignant Melanoma
Head and Neck Cancer
Breast Cancer
Renal Cell Carcinoma
Prostate Cancer.
ISBN 978-3-642-78868-0
Article number 9783642788680
Media type Book
Edition number Softcover reprint of the original 1st ed. 1994
Copyright year 2012
Publisher Springer, Berlin
Length VII, 75 pages
Illustrations VII, 75 p.
Language English