This book analyzes the basic science and treatment of male factor infertility with Dr. Silber's characteristic honesty and clear thinking. It describes finally what works and what doesn't work. It will inspire everyone in reproductive medicine (Gynecologists, Urologists, Embryologists and Endocrinologists) who wish to better understand male infertility.

Part 01- HOW THE THE TESTIS WORKS Basic Science of the Testis

1. Testis development embryology and anatomy
2. Decent from the abdomen of the fetal testis to the scrotum
3. Adult testis anatomy
4. Structure of the seminiferous tubules
5. Blood supply to the testis
6. Histology of the testis and spermatogenesis
7. Hormonal regulation of spermatogenesis
8. Meiosis
Part 02- EVALUATION AND TREATMENT OF MALE INFERTILITY
9. Evaluation of the male
10. Treatment of male infertility
11. Azoospermia
12. Genetics of male infertility and intracytoplasmic sperm injection
13. Donor Sperm.- 
14. Sperm Cryopreservation.-  15. Varicocele.-  16. Kallman's Syndrome and Hypopituitarism
Part 03- NEW FRONTIERS: Y CHROMOSOMES IN THE ERA OF ICSI, AND SPERMATOGENIC STEM CELL TRANSPLANTATION
17. Y chromosome in the ear of ICSI
18.Spermatogeneic stem cell culture and transplantation
19. Sperm from Skin Cells: Embryonic Stem Cells, and Differentiation to Eggs and Sperm
20. Identification of SSC's (Spermatogonial Stem Cells) and Genetic Control of All Stages of Spermatogenesis