Interferons were among the first cytokines to be studied clinically in recombinant form in the 1980s, beginning a new era of pharmacotherapy in internal medicine. Interferons were soon employed in the treatment of tumors and it was shown that those hematopoietic neoplasias which had been difficult to treat with chemotherapy responded well to interferon treatment. In the present volume, renowned international authors update the importance of interferons in various fields of internal medicine, dermatology, and urology. The book also contains a general introduction into the classification, structure, and mode of action of interferons. Further chapters discuss the range of side effects of these substances and point out possible focuses of further clinical interferon research.

Distribution of Interferon-?2 Genes in Humans

The Role of Endogenous Interferon-? in HIV Infection and Autoimmune Diseases - An Overview
Treatment of Chronic Viral Hepatitis with Interferon-?
Interferon Therapy of Neuroendocrine Tumours
Use of Interferon-? in the Treatment of Chronic Myelogenous Leukemia
Interferon Therapy of Essential Thrombocythemia and Polycythemia Vera
Follicular Lymphomas: Morphology, Prognostic Factors and Treatment
Treatment Strategies in Multiple Myeloma: Biotherapy with Interferons
Treatment Options for Hairy Cell Leukemia
Alpha-Interferon and Bone Marrow or Peripheral Blood Stem Cell Transplantation
Cutaneous Lymphomas: A Heterogenous Group of Lymphoproliferative Disorders At Least in Part Sensitive to Interferon Treatment
Current Therapy Strategies for Malignant Melanoma with Special Regard to Immunotherapy with Cytokines
Interferons in Kaposi's Sarcoma
Interferons in the Treatment of Genitorurinary Tumors
Adverse Effects of Interferon Treatment
Interferon-?: Its Current Clinical Utility and Future Perspectives.