Lung Transplantation

Lung Transplantation

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Clinical lung transplantation has seen an early start within the history of solid organ trans plantation, marked by the 1963 first lung transplant by James D. Hardy. This was prompted by the seemingly easy way of joining the transplanted organ to the recipient by me ans of a few well-defined anastomoses, i.e. bronchus, pulmonary artery and pulmonary vein carry ing left atrial cuff. The following decade thus witnessed a number of such mostly unilateral lung transplants in several centres, in Germany represented by the two only lung transplants performed by E. S. Bücherl, then at the Neukölln City Hospital in Berlin in 1969. As with most other such attempts these two patients suffered early and lethai graft failure. There was only one single lung transplant patient who lived up to ten months after the transplant at Gent, Belgium, having been operated on by Derom in 1969. The alm ost universal failure during this initial phase was attributed to bronchial anasto motic insufficiency, pulmonary infection of either the transplanted lung or the left-in-place contralateral lung and a far-reaching lack of knowledge how to cope with transplant rejec tion. In the early 1970s it had become gene rally accepted that lung transplantation could not be performed successfully.

Single versus bilateral lung transplantation
Rejection and infection after lung transplantation
Management of bronchial complications in lung transplantation
Lung transplantation in cystic fibrosis
Lung transplantation for acute pulmonary failure
Lung and heart-lung transplantation with direct bronchial artery revascularization.
ISBN 978-3-662-04679-1
Article number 9783662046791
Media type Book
Edition number Softcover reprint of the original 1st ed. 2003
Copyright year 2013
Publisher Steinkopff
Length VII, 69 pages
Illustrations VII, 69 p. 40 illus.
Language English