Mathematical Modelling of Haemodialysis

Cardiovascular Response, Body Fluid Shifts, and Solute Kinetics

Mathematical Modelling of Haemodialysis

Cardiovascular Response, Body Fluid Shifts, and Solute Kinetics

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Beginning with an introduction to kidney function, renal replacement therapies, and an overview of clinical problems associated with haemodialysis, this book explores the principles of the short-term baroreflex regulation of the cardiovascular system and the mechanisms of water and solute transport across the human body from a mathematical model perspective. It synthesizes theoretical physiological concepts and practical aspects of mathematical modelling needed for simulation and quantitative analysis of the haemodynamic response to dialysis therapy.

Including an up-to-date review of the literature concerning the modelled physiological mechanisms and processes, the book serves both as an overview of transport and regulatory mechanisms related to the cardiovascular system and body fluids and as a usefulreference for the study and development of mathematical models of dynamic physiological processes.

Mathematical Modelling of Haemodialysis: Cardiovascular Response, Body Fluid Shifts, and Solute Kinetics is intended for researchers and graduate students in biomedical engineering, physiology, or medicine interested in mathematical modelling of cardiovascular dynamics and fluid and solute transport across the human body, both under physiological conditions and during haemodialysis therapy.



Introduction to renal replacement therapies and mathematical modelling in physiology

Mathematical modelling in physiology.- Model structure, equations and parameters.- Model analysis and validation.- Simulation results and model outcomes.- Conclusions, challenges and future research directions.


ISBN 978-3-030-21412-8
Article number 9783030214128
Media type Book
Copyright year 2020
Publisher Springer, Berlin
Length XVII, 156 pages
Illustrations XVII, 156 p. 43 illus., 38 illus. in color.
Language English