Organolithiums in Enantioselective Synthesis
Organolithiums in Enantioselective Synthesis
Organolithium chemistry occupies a central position in the selective construction of C-C bonds in both simple and complex molecules. Paralleling the surge of interest in methods for asymmetric synthesis, the use of organolithiums in enantioselective synthesis has witnessed spectacular advances in a little over a decade. This volume is the first dedicated to a comprehensive coverage of this important area. It is designed to provide graduate students and researchers with a rich source of essential information on synthesising molecules in an enantioselective manner using organolithiums, and be an inspiration for future developments. Following an overview chapter summarising the key milestones, successive chapters, each written by leading experts in their field, critically survey all the major areas of progress.
Overview of Organolithium-Ligand Combinations and Lithium Amides for Enantioselective Processes
Enantioselective Addition of Organolithiums to C=O Groups and EthersEnantioselective Conjugate Addition and 1,2-Addition to C=N of Organolithium Reagents
Enantioselective Synthesis by Lithiation Adjacent to Oxygen and Electrophile Incorporation
Enantioselective Synthesis by Lithiation Adjacent to Nitrogen and Electrophile Incorporation
Enantioselective Synthesis by Lithiation Adjacent to Sulfur, Selenium or Phosphorus, or without an Adjacent Activating Heteroatom
Enantioselective Synthesis by Lithiation Adjacent to Oxygen and Subsequent Rearrangement
Enantioselective Synthesis by Lithiation to Generate Planar or Axial Chirality
Enantioselective Carbolithiations.
Hodgson, David M.
| ISBN | 978-3-662-14612-5 |
|---|---|
| Article number | 9783662146125 |
| Media type | Book |
| Edition number | Softcover reprint of the original 1st ed. 2003 |
| Copyright year | 2013 |
| Publisher | Springer, Berlin |
| Length | IX, 320 pages |
| Illustrations | IX, 320 p. |
| Language | English |
