Principles of Bioenergetics summarizes one of the quickly growing branches of modern biochemistry. Bioenergetics concerns energy transductions occurring in living systems and this book pays special attention to molecular mechanisms of these processes. The main subject of the book is the "energy coupling membrane" which refers to inner membranes of intracellular organelles, for example, mitochondria and chloroplasts. Cellular cytoplasmic membranes where respiratory and photosynthetic energy transducers, as well as ion-transporting ATP-synthases (ATPases) are also part of this membrane. Significant attention is paid to the alternative function of mitochondria as generators of reactive oxygen species (ROS) that mediate programmed death of cells (apoptosis and necrosis) and organisms (phenoptosis). The latter process is considered as a key mechanism of aging which may be suppressed by mitochondria-targeted antioxidants.

Part I: General Aspects of Bioenergetics: Introduction

Part II: Generators of Proton Potential: Chlorophyll-Based Generators of Proton Potential
Organotrophic Energetics
The Respiratory Chain
Structure of Respiratory Chains of Procaryotes and Mitochondria of Protozoa, Plants, and Fungi.- Bacteriorhodopsin
Part III: Consumers
Driven Chemical Work
Driven Mechanical Work: Bacterial Motility
Driven Osmotic Work
Energy Source for Heat Production
Part IV Interaction and Regulation of Proton Potential Generators and Consumers: Regulation, Transmission, and Buffering of Proton Potential
Part V The Sodium World: Generators
Part VI Mitochondrial Reactive Oxygen Species and Mechanisms of Aging: Concept of Aging as a Result of Programmed Slow Poisoning of Organism with Mitochondrial Reactive Oxygen Species
Possible Medical Applications of Membrane Bioenergetics: Mitochondria-Targeted Antioxidants as Geroprotectors
Appendices.