Side Reactions in Organic Synthesis

A Guide to Successful Synthesis Design

Side Reactions in Organic Synthesis

A Guide to Successful Synthesis Design

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Most syntheses in the chemical research laboratory fail and usually require several attempts before proceeding satisfactorily. Failed syntheses are not only discouraging and frustrating, but also cost a lot of time and money. Many failures may, however, be avoided by understanding the structure-reactivity relationship of organic compounds.
This textbook highlights the competing processes and limitations of the most important reactions used in organic synthesis. By allowing chemists to quickly recognize potential problems this book will help to improve their efficiency and success-rate. A must for every graduate student but also for every chemist in industry and academia.
Contents:
1 Organic Synthesis: General Remarks
2 Stereoelectronic Effects and Reactivity
3 The Stability of Organic Compounds
4 Aliphatic Nucleophilic Substitutions: Problematic Electrophiles
5 The Alkylation of Carbanions
6 The Alkylation of Heteroatoms
7 The Acylation of Heteroatoms
8 Palladium-Catalyzed C-C Bond Formation
9 Cyclizations
10 Monofunctionalization of Symmetric Difunctional Substrates
ISBN 9783527604982
Article number 9783527604982
Media type eBook - PDF
Copyright year 2006
Publisher Wiley-VCH
Length 389 pages
Language English
Copy protection Adobe DRM