The Molecular Genetics of Lung Cancer

The Molecular Genetics of Lung Cancer

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Lung cancer is the leading cause of cancer mortality in Western countries. It also provides an archetypal example of how inherited predisposing genetic variants may interact with an environmental influence (smoking) to modulate individual cancer risk.

The Molecular Genetics of Lung Cancer describes how the new techniques, methods and approaches of molecular genetics are being used to unravel the complexities of the mechanisms underlying lung tumorigenesis by analysis at the DNA, RNA and protein levels with potentially important implications for tumour classification, diagnosis, prognosis and treatment as well as providing new insights into how lung tumours arise and how they progress to malignancy.



An Introduction to the Molecular Basis of Cancer
Lung Cancer: Setting the Scene
Genes Involved in Sporadic Forms of Lung Cancer
Somatic Mutation in Lung Cancer
Genetic Approaches to Studying the Association Between Smoking and Lung Cancer
Evidence for Genetic Susceptibility to Lung Cancer Derived from Polymorphism-disease Association Studies
Gene Expression Studies in Lung Cancer
Lung Cancer Pathogenesis and Future Prospects for Treatment and Prevention.
ISBN 978-3-642-06190-5
Article number 9783642061905
Media type Book
Copyright year 2010
Publisher Springer, Berlin
Length XVI, 392 pages
Illustrations XVI, 392 p. 34 illus., 13 illus. in color.
Language English