This book contains the contribution to the 37th Hemophilia Symposium, Hamburg 2006. The main topics are epidemiolgy, treatment of inhibitors in hemophiliacs, hemophilic arthropathy and synovitis, relevant hemophilia treatment 2006, and pediatric hemostasiology. The volume is rounded off by numerous free papers and posters on hemophilia, casuistics, and diagnostics.

Johann Lukas Schoenlein Prize 2006

Johann Lukas Schoenlein Prize 2006
Epidemiology
HIV Infection and Causes of Death in Patients with Hemophilia in Germany (Year 2005/2006 Survey)
Hemophilia Registry of the Medical Committee of the Swiss Hemophilia Association - Update and Annual Survey 2006
Treatment of Inhibitors in Hemophiliacs
Detection of Factor VIII-Specific Memory B Cells in Patients with Hemophilia A and Factor VIII Inhibitors
Novel Strategies for FVIII: Half-life Prolongation
Hemophilic Arthropathy and Synovitis
Predictive Parameters of Fitness in Hemophiliac Children
Hemophilia and Exercise Project (HEP) Conception and Contents of a "Programmed Sports Therapy" for Hemophilic Patients
Results of German Hemophiliacs Self-Assessment of Health and Social Status: With Emphasis on Orthopedic Function
Relevant Hemophilia Treatment 2006
Developing a German Hemophilia Register
Pediatric Hemostasiology
Thrombin Generation in Children with Hemophilia and VWD - Comparing a Fluorimetric Method and ROTEM
Thrombin Generation in Severely Obese Children
Protein C Promoter Genotypes Associate with Susceptibility, Development of Sepsis, and Lower Blood Pressure in Young Children with Systemic Meningococcemia
Life of Teenage Hemophiliacs
Free Lectures
Monocytes Enhance rVIIa Induced Thrombin Generation in Absence of Platelets and Microparticles
Mutation Detection Rate in Female Patients with Reduced Factor VIII Activity and Negative Family History for Hemophilia A
Investigation of Underlying Reasons of Factor VIII Deficiency in Hemophilia A Patients with Undetectable Mutations in the F8 Gene
Monitoring of Antiplatelet Therapy Using Whole Blood Aggregometry: Experiences and Approaches to Dose Adaptation
Poster
NoComplications in Switching from Recombinate to Advate - a Prospective Surveillance in 22 Children
Epidemiology and Treatment of Hemophilia A, B and von Willebrand Disease of Type 3 in the Eastern Part of German
Database Management System for a Hemophilia Comprehensive Care Center
Hepatocellular Carcinoma in Patients with Hemophilia and Chronic Hepatitis C Infection
Elucidation of Gross Genomic Rearrangements Involving Large Deletions in the Clotting Factor VIII Gene
The Centro American Hemophilia Registry, of the CARS Hemophilia Group - Update September 2006
Two Examples of the Influence of Psychological Stress on the von Willebrand Factor Activity
Efficacy of Chronic Hepatitis C Treatment in Hemophilic Patients During the Last 10 Years: a Single Center Experience
Dynamic of Thrombin Generation in Patients with Severe Hemophilia A
Hemophilia and Exercise Project (HEP): Effects of a Two-Year Sports Therapy on Physical Activity Behavior and Bleeding Frequency by Persons with Hemophilia
Hemophilia Summer Camp in Germany, 1996-2005
Impact of Hemophilia on the Psychological Health of Hemophilia Patients in Romania
Starter-Kit for Patients Suffering from Hemophilia - A Project Initiated by the German Hemophilia Assistant Committee
Documentation in Hemophilia Treatment
Short-time Prophylaxis with FEIBA in Three Patients with Hemophilia A and High Titer Inhibitors
Successful Treatment of a Patient with High Titer Acquired Factor VIII Inhibitor (114 BU) with Rituximab
Preoperative Arterial Embolization of a Hemophilic Pseudo Tumor before Osteosynthesis in a Patient with Hemophilia A and Pathological Femoral Fracture
Successful Liver Transplantation in Two Patients with Severe Hemophilia A
Out from the Cold: Severe Erythema and ClumpedRed Cells
Acquired Glanzmann Thrombasthenia in a Patient with Myelodysplastic Syndrome
Case Report of an Acquired Inhibitor Against Factor XIII
Elbow Endoprosthesis in Hemophilic Arthropathy
Pseudohomozygous APC Resistance Report on Two Patients and a Novel Mutation in the Factor V Gene
Pseudo-Homozygous APC Resistance Due to Coinheritance of Heterozygous Factor V - R506Q and Type I Deficiency Associated with Thrombosis
Three Cases of In-stent Thrombosis in Patients with Clopidogrel Non-response
Thrombin Generation in Pregnancy
Thrombin Generation - Comparison of ROTEM and Technothrombin TGA
Multiple Electrode Aggregometry in Patients on Chronic Aspirin and/or Clopidogrel Treatment
Endogenous Thrombin Potential in Women with Recurrent Miscarriage and/or Repeated In-Vitro-Fertilization Failure
One Year TTP Diagnosis in the Central Laboratory of the University of Mainz
Venous Thromboembolism - A Metabolic Disease?
Structural Investigation of Two Novel Mutations in Coagulation Factor V by Molecular Modeling
High Levels of Human Factor IX Transgene Expression in Mice Increase Blood Procoagulant Activity
Factor VII Deficiency: Clinical Manifestation and Molecular Genetics of 718 Subjects with FVII Gene Mutations
Therapeutical Options for Congenital FVII Deficiency - The HK 7 Project of the International Greifswald Registry of the Congenital FVII Deficiency (GR-HK-7)
Characterization of a Mutation in Exon 1 of the FVII Gene - a Case of RNA Editing?
Analysis of the Biological Importance of the VKORC1 Gene via Knock-Out Mice
In Vivo-Assay for Warfarin-Resistance by Coexpression of VKORC1 and Vitamin K-Dependent Coagulation Factors
Functional Promoter Polymorphism in the VKORC1 Gene is no Major Genetic Determinant for Vitamin KDependent Coagulation Factor Activity
Influence of VKORC1 Haplotypes on Cardiovascular Disease
Creation and Characterization of a Knock-Out Mouse for the VKORC1L1-Gene
Novel Variants in VKORC1 - the Target Protein of Cumarin-Type Anticoagulants - in Rodents from Warfarin-Resistance Areas in Europe, Asia and America
Recombinant Expression and 3D-Modelling of C1-Inhibitor Mutants
Five Novel Mutations in F13B Gene Resulting in Mild FXIII Deficiency
Idiopathic Thrombocytopenic Purpura in Children: Predictive Factors for the Outcome
Preoperative DDAVP-Testing in Patients with von Willebrand Disease.