5-HT4 Receptors in the Brain and Periphery

5-HT4 Receptors in the Brain and Periphery

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This book provides a comprehensive, up-to-date review of the distribution, pharmacology and physiology of central 5-hydroxytryptamine (5-HT)4 receptors. The 5-HT receptor subtypes exhibit a unique pharmacology, distribution and function, of which the 5-HT4 receptor has been one of the most intensively studied in recent years, both from a basic research standpoint and as a target for novel therapeutics.

1. Medicinal Chemistry of 5-HT4 Receptor Ligands
2. Molecular Biology of 5-HT4 Receptors
3. Localization of 5-HT4 Receptors in Vertebrate Brain and Their Potential Behavioral Roles
4. Central 5-HT4 Receptors: Electrophysiology
5. Neurochemical Consequences Following Pharmacological Manipulation of Central 5-HT4 Receptors
6. 5-Hydroxytryptamine and Human Heart Function: The Role of 5-HT4 Receptors
7. 5-HT4 Receptors in Gastrointestinal Tract
8. 5-HT4 Receptors in Lower Urinary Tract Tissues
9. The 5-HT4 Receptor in the Adrenal Gland
10. Therapeutic Applications of 5-HT4 Receptor Agonists and Antagonists.
ISBN 978-3-540-64164-3
Artikelnummer 9783540641643
Medientyp Buch
Copyrightjahr 1998
Verlag Springer, Berlin
Umfang XIII, 229 Seiten
Abbildungen XIII, 229 p. 19 illus.
Sprache Englisch