Now in a revised and expanded third edition, this case-based guide emphasizes the latest investigative advances in both imaging and molecular diagnostics and new treatment approaches for a wide variety of common and complex endocrine conditions. 
Utilizing unique clinical case histories, each main endocrine condition and disorder is curated by a senior Section Editor with an introduction to his or her area covering both physiology and pathophysiology. This introductory chapter is followed by a number of case histories written by invited experts and designed to cover the important relevant pathophysiology, following a consistent chapter format for ease of use, including bulleted objectives, case presentations, review of the diagnosis, lessons learned, and 3-5 multiple-choice review questions. Section headings include the pituitary, thyroid (overactivity, underactivity and cancer) and parathyroid, adrenal disorders, metabolic bone disease, type 2 diabetes, lipid abnormalities, obesity, and pregnancy. Topics new to this edition include PCOS, transgender medicine and the endocrine effects of viral infections.
With a focus on covering major parts of the APDEM curriculum, A Case-Based Guide to Clinical Endocrinology remains a tremendous resource for junior and veteran clinicians alike. 

<b>Part I. Pituitary Disorders

</b>Introduction to Pituitary Disorders
Pituitary Tumor Behavior and Disease Severity in Patients with Acromegaly
Abrupt Weight Gain, Hypertension and Severe Hypokalemia in a Young Male
Dopamine Agonist-Induced Impulse Control Disorders
<b>Part II. Thyroid Overactivity.-</b> Introduction to Thyroid Overactivity
Immunoglobin G4 and Grave's Orbitopathy
Subclinical Hyperthyroidism: Case Report and Review of the Literature
A Case of Gestational Thyrotoxicosis
<b>Part III. Thyroid Underactivity.-</b> Introduction to Thyroid Underactivity
Managing Hypothyroidism: Increasing Levothyroxine Requirements
Gastrointestinal Disease and Levothyroxine Absorption
Drug-Induced Central Hypothyroidism
<b>Part IV. Thyroid Cancer.-</b> Introduction to Thyroid Cancer
Papillary Thyroid Cancer
Anaplastic Thyroid Carcinoma
Medullary Thyroid Carcinoma
<b>Part V. Adrenal Disorders.-</b> Introduction to Adrenal Disorders
Adrenal Incidentalomas andAutonomous Cortisol Secretion
Pheochromocytoma
Ectopic ACTH Syndrome
<b>Part VI. Primary Hyperparathyroidism.-</b> Introduction to Primary Hyperparathyroidism
Cinacalcet Use in Primary Hyperparathyroidism
A Case of Apparently Sporadic Primary Hyperparathyroidism Carrying a Germline Mutation of CDC73 Gene
Challenges in the Preoperative Localization of Hyperfunctioning Parathyroid Tissue in a Patient with Primary Hyperparathyroidism
<b>Part VII. Metabolic Bone Diseases.-</b> Introduction to Metabolic Bone Diseases
Type 2 Diabetes and Bone
Hypercalcemia and High Bone Mineral Density
Rare Presentation of Severe Pediatric Rickets
<b>Part VIII. Endocrine Disorders in Men.-</b> Introduction to Endocrine Disorders in Men
Adult Onset Hypogonadism
Congenital Hypogonadotropic Hypogonadism
Klinefelter Syndrome
<b>Part IX. Endocrine Disorders in Pregnancy.-</b> Introduction to Endocrine Disorders in Pregnancy
Prolactinoma in Pregnancy
Adrenal Insufficiency in Pregnancy
Pheochromocytoma in Pregnancy
Diagnosis and Management of Thyroid Cancer in Pregnant Women
<b>Part X. Type 2 Diabetes Mellitus
</b>Introduction to Type 2 Diabetes Mellitus
Initial Diagnosis and Management of Type 2 Diabetes Mellitus
Outpatient Management of Type 2 Diabetes Mellitus
Inpatient Management of Type 2 Diabetes Mellitus
<b>Part XI. Lipid Abnormalities.-</b> Introduction to Lipid Abnormalities
A Case of Heterozygous Familial Hypercholesterolemia: Success of Long-term Management
A 53 Year Old Man with Severe Combined Hyperlipidemia and Multiple Medication Sensitivities
Familial Partial Lipodystrophy Presenting as Extreme Hypertriglyceridemia and Acute Pancreatitis
<b>Part XII. Obesity.-</b> Introduction to Obesity
Obesity Assessment and Management Using an Illustrative Case in Severe Mental Illness
Obesity Management and Use of Very Low Energy Diets
Obesity Case Management: Bariatric Surgery
<b>Part XIII. Polycystic Ovary Syndrome.-</b> Introduction to Polycystic Ovary Syndrome.- PCOS and Hirsuties.- PCOS and Reproduction.- PCOS and Insulin Resistance.- PCOS and the Metabolic Syndrome.- <b>Part XIV. Transgender Medicine.-</b> Introduction to Transgender Medicine
Trans-Masculine Therapy
Peri-operative Estrogen Considerations for Transgender Women Undergoing Vaginoplasty
Feminizing Gender-Affirming Hormone Therapy: Special Considerations for Older Adults
<b>Part XV. Endocrine Effects in Virus Infections.-</b> Introduction to Endocrine Effects in Virus Infections
Adrenal Function in HIV Infection
HIV Infection and Lipodystrophy
Endocrinopathies of SARS-CoV-2.