Now in a revised and expanded third edition, this case-based guide emphasizes the latest investigative advances in both imaging and molecular diagnostics and new treatment approaches for a wide variety of common and complex endocrine conditions. 
Utilizing unique clinical case histories, each main endocrine condition and disorder is curated by a senior Section Editor with an introduction to his or her area covering both physiology and pathophysiology. This introductory chapter is followed by a number of case histories written by invited experts and designed to cover the important relevant pathophysiology, following a consistent chapter format for ease of use, including bulleted objectives, case presentations, review of the diagnosis, lessons learned, and 3-5 multiple-choice review questions. Section headings include the pituitary, thyroid (overactivity, underactivity and cancer) and parathyroid, adrenal disorders, metabolic bone disease, type 2 diabetes, lipid abnormalities, obesity, and pregnancy. Topics new to this edition include PCOS, transgender medicine and the endocrine effects of viral infections.
With a focus on covering major parts of the APDEM curriculum, A Case-Based Guide to Clinical Endocrinology remains a tremendous resource for junior and veteran clinicians alike. 

Part I. Pituitary Disorders

Introduction to Pituitary Disorders
Pituitary Tumor Behavior and Disease Severity in Patients with Acromegaly
Abrupt Weight Gain, Hypertension and Severe Hypokalemia in a Young Male
Dopamine Agonist-Induced Impulse Control Disorders
Part II. Thyroid Overactivity.- Introduction to Thyroid Overactivity
Immunoglobin G4 and Grave's Orbitopathy
Subclinical Hyperthyroidism: Case Report and Review of the Literature
A Case of Gestational Thyrotoxicosis
Part III. Thyroid Underactivity.- Introduction to Thyroid Underactivity
Managing Hypothyroidism: Increasing Levothyroxine Requirements
Gastrointestinal Disease and Levothyroxine Absorption
Drug-Induced Central Hypothyroidism
Part IV. Thyroid Cancer.- Introduction to Thyroid Cancer
Papillary Thyroid Cancer
Anaplastic Thyroid Carcinoma
Medullary Thyroid Carcinoma
Part V. Adrenal Disorders.- Introduction to Adrenal Disorders
Adrenal Incidentalomas andAutonomous Cortisol Secretion
Pheochromocytoma
Ectopic ACTH Syndrome
Part VI. Primary Hyperparathyroidism.- Introduction to Primary Hyperparathyroidism
Cinacalcet Use in Primary Hyperparathyroidism
A Case of Apparently Sporadic Primary Hyperparathyroidism Carrying a Germline Mutation of CDC73 Gene
Challenges in the Preoperative Localization of Hyperfunctioning Parathyroid Tissue in a Patient with Primary Hyperparathyroidism
Part VII. Metabolic Bone Diseases.- Introduction to Metabolic Bone Diseases
Type 2 Diabetes and Bone
Hypercalcemia and High Bone Mineral Density
Rare Presentation of Severe Pediatric Rickets
Part VIII. Endocrine Disorders in Men.- Introduction to Endocrine Disorders in Men
Adult Onset Hypogonadism
Congenital Hypogonadotropic Hypogonadism
Klinefelter Syndrome
Part IX. Endocrine Disorders in Pregnancy.- Introduction to Endocrine Disorders in Pregnancy
Prolactinoma in Pregnancy
Adrenal Insufficiency in Pregnancy
Pheochromocytoma in Pregnancy
Diagnosis and Management of Thyroid Cancer in Pregnant Women
Part X. Type 2 Diabetes Mellitus
Introduction to Type 2 Diabetes Mellitus
Initial Diagnosis and Management of Type 2 Diabetes Mellitus
Outpatient Management of Type 2 Diabetes Mellitus
Inpatient Management of Type 2 Diabetes Mellitus
Part XI. Lipid Abnormalities.- Introduction to Lipid Abnormalities
A Case of Heterozygous Familial Hypercholesterolemia: Success of Long-term Management
A 53 Year Old Man with Severe Combined Hyperlipidemia and Multiple Medication Sensitivities
Familial Partial Lipodystrophy Presenting as Extreme Hypertriglyceridemia and Acute Pancreatitis
Part XII. Obesity.- Introduction to Obesity
Obesity Assessment and Management Using an Illustrative Case in Severe Mental Illness
Obesity Management and Use of Very Low Energy Diets
Obesity Case Management: Bariatric Surgery
Part XIII. Polycystic Ovary Syndrome.- Introduction to Polycystic Ovary Syndrome.- PCOS and Hirsuties.- PCOS and Reproduction.- PCOS and Insulin Resistance.- PCOS and the Metabolic Syndrome.- Part XIV. Transgender Medicine.- Introduction to Transgender Medicine
Trans-Masculine Therapy
Peri-operative Estrogen Considerations for Transgender Women Undergoing Vaginoplasty
Feminizing Gender-Affirming Hormone Therapy: Special Considerations for Older Adults
Part XV. Endocrine Effects in Virus Infections.- Introduction to Endocrine Effects in Virus Infections
Adrenal Function in HIV Infection
HIV Infection and Lipodystrophy
Endocrinopathies of SARS-CoV-2.