The aim of "ALERT - Adverse Late Effects of Cancer Treatment" is to offer a coherent multidisciplinary approach to the care of cancer survivors. Volume 1 of this two-volume work focuses on the general concepts and principles relevant to late effects and on the dynamic interplay of molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Chapters are also included on legal issues, economic aspects, nursing, psychological issues and quality of life. Volume 2 comprehensively documents potential late effects in all the normal tissue sites in the human body. The detection, diagnosis, management and prevention of effects are all considered in detail, and prognostic outcomes are discussed. Radiation risk factors and interactions with chemotherapy effects are clearly presented. Numerous supportive illustrations and tables are included, and it is anticipated that this textbook will become the gold standard in the field.

Volume 1: BioContinuum of Effects of Multimodal Therapy

BioMolecular Mechanisms and Pathways of Normal Tissue Damage
BioPathology of Radiation and Chemotherapy
BioImaging of the Longitudinal Normal Tissue Injury
BioScoring Systems for Acute and Late Effects
BioPediatric Complexities of Growth and Development
Bioepidemiology
BioGenetic and Host Implications
Radiotherapy-Induced Biocarcinogenesis and Leukemogenesis
BioManagement and BioPrevention.-BioSurveillance and Longitudinal Lifelong Guidelines
Specific Precept: Medical Legal Issues: Malpractice Issues
Insurance, Economics: Cost of Care
Nursing
Psychologic Issues
Social Worker Issues: Quality of Life and Activities of Daily Living
Subject Index
List of Contributors
Contents of Volume 2 Specific Normal Tissue Sites.

Volume 2: Central and Peripheral Nervous System
Special Sensory Organ Systems
Upper Digestive System,- Upper Respiratory System
Respiratory System
Cardiovascular System
Digestive System
Major Digestive Glands
Genitourinary System
Male Genital System
Female Genital System
Integument (Appendages) System
Musculoskeletal System
Hematopoetic System
Lymphoid System
Endocrine System
Subject Index
List of Contributors
Contents of Volume 1 General Concepts and Principles.