The new edition of this well-received book provides a timely update of current knowledge on the biology, disease classification, and treatment of the acute leukemias - acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Throughout, the focus is on the provision of state of the art information and guidance that will meet the needs of clinicians. Chapters have been extensively revised to take into account advances in understanding and management that have been achieved over the past few years. In addition, new chapters have been included on selection of AML patients for therapy, a broader discussion of stem cell transplantation in AML, the role of immunotherapy in ALL, the approach to newly diagnosed pediatric ALL, and the diagnosis and management of BCR-ABL-like ALL. New therapies, including investigational ones, are fully covered. As progress continues in the management of acute leukemias this book will be a valuable asset for clinicians at all levels of experience.

Part I Acute Myeloid Leukemia

Acute Myeloid Leukemia: Epidemiology and Etiology
Clinical Presentation, Diagnosis and Classification of Acute Myedloid Leukemia
Selection of Patients for Therapy
Therapy of Newly Diagnosed AML
Management of Relapsed and Refractory AML
Stem cell Transplant in AML
Investigational Therapies in AML
Acute Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia: Epidemiology abnd Etiology
Molecular Biology and Genetics
Acute Lymphoblastic Leukemia: Clinical Presentation, Diagnosis, and Classification
Therapy of Newly Diagnosed Adult ALL
Approach to Newly Diagnosed Pediatric and AYA ALL
The Role of Immunotherapy in ALL
STem Cell Transplantation in the Treatment of ALL
The Significance of Minimal Residual Disease in Acute Lymphoblastic Leukemia
Philadelphia Chromosome - Positive Acute Lymphoblastic Leukemia
BCR-ABL-like ALL: Diagnosis and Management
Burkitt's Acute Lymphoblastic Leukema in Adults
Treatment of Lymphoblastic Lymphoma in Adults
Central Nervous System Involovment in Adult Acute Lymphocytic Leukemia
Management of Relapsed and Refractory ALL
Emergencies in Acute Lymphoblastic Leukema
Investigational Therapies in ALL