This book provides a perspective on the current status of bioimaging technologies developed to assess the quality of musculoskeletal tissue with an emphasis on bone and cartilage. It offers evaluations of scaffold biomaterials developed for enhancing the repair of musculoskeletal tissues. These bioimaging techniques include micro-CT, nano-CT, pQCT/QCT, MRI, and ultrasound, which provide not only 2-D and 3-D images of the related organs or tissues, but also quantifications of the relevant parameters. The advance bioimaging technologies developed for the above applications are also extended by incorporating imaging contrast-enhancement materials. Thus, this book will provide a unique platform for multidisciplinary collaborations in education and joint R&D among various professions, including biomedical engineering, biomaterials, and basic and clinical medicine.

Perspectives of Advances in Musculoskeletal and Scaffold Biomaterial Imaging Technologies and Applications

Perspectives on Advances in Bone Imaging for Osteoporosis
Bone Structure and Biomechanical Analyses Using Imaging and Simulation Technology
Imaging Technologies for Orthopaedic Visualization and Simulation
In-Vivo Bone Mineral Density and Structures in Humans: From Isotom Over Densiscan to Xtreme-CT
Calibration of Micro-CT Data for Quantifying Bone Mineral and Biomaterial Density and Microarchitecture
Repositioning of the Region of Interest in the Radius of the Growing Child in Follow-up Measurements by pQCT
Non-invasive Bone Quality Assessment Using Quantitative Ultrasound Imaging and Acoustic Parameters
Cortical Bone Mineral Status Evaluated by pQCT, Quantitative Backscattered Electron Imaging and Polarized Light Microscopy
High-Fidelity Histologic Three-Dimensional Analysis of Bone and Cartilage
Application of Laser Scanning Confocal Microscopy in Musculoskeletal Research
Fiber-optic Nano-biosensors and Near-Field Scanning Optical Microscopy for Biological Imaging
Changes of Biological Function of Bone Cells and Effect of Anti-osteoporosis Agents on Bone Cells
Bone Histomorphometry in Various Metabolic Bone Diseases Studied by Bone Biopsy in China
Cell Traction Force Microscopy
Contrast-Enhanced Micro-CT Imaging of Soft Tissues
Materials Selection and Scaffold Fabrication for Tissue Engineering in Orthopaedics
Quantification of Porosity, Connectivity and Material Density of Calcium Phosphate Ceramic Implants Using Micro-Computed Tomography
Bone Densitometries in Assessing Bone Mineral and Structural Profiles in Patients with Adolescent Idiopathic Scoliosis
Application of Nano-CT and High-Resolution Micro-CT to Study Bone Quality and Ultrastructure, Scaffold Biomaterials and Vascular Networks
Bio-imaging Technologies in Studying Bone-Biomaterial Interface: Applications in Experimental Spinal Fusion Model
Assessment of Bone, Cartilage, Tendon and Bone Cells by Confocal Laser Scanning Microscopy
Specific Applications of Advances in Musculoskeletal and Scaffold Biomaterial Imaging Technologies
TEM Study of Bone and Scaffold Materials
Material and Structural Basis of Bone Fragility: A Rational Approach to Therapy
Application of Micro-CT and MRI in Clinical and Preclinical Studies of Osteoporosis and Related Disorders
CT-Based Microstructure Analysis for Assessment of Bone Fragility
Discrimination of Contributing Factors to Bone Fragility Using vQCT In Vivo
Osteoporosis Research with the vivaCT40
Mechanical Properties of Vertebral Trabeculae with Ageing Evaluated with Micro-CT
MRI Evaluation of Osteoporosis
Multiple Bio-imaging Modalities in Evaluation of Epimedium-Derived Phytoestrogenic Fraction for Prevention of Postmenopausal Osteoporosis
Areal and Volumetric Bone Densitometry in Evaluation of Tai Chi Chuan Exercise for Prevention of Postmenopausal Osteoporosis
Enhancement of Osteoporotic Bone Using Injectable Hydroxyapatite in OVX Goats Evaluated by Multi-imaging Modalities
Quality of Healing Compared Between Osteoporotic Fracture and Normal Traumatic Fracture
Monitoring Fracture Healing Using Digital Radiographies
Fracture Callus Under Anti-resorptive Agent Treatment Evaluated by pQCT
Volumetric Measurement of Osteonecrotic Femoral Head Using Computerized MRI and Prediction For Its Mechanical Properties
Biomedical Engineering in Surgical Repair of Osteonecrosis: the Role of Imaging Technology
Contrast-Enhanced MRI and Micro-CT Adopted for Evaluationof a Lipid-Lowering and Anticoagulant Herbal Epimedium-Derived Phytoestrogenic Extract for Prevention of Steroid-Associated Osteonecrosis
Nanomechanics of Bone and Bioactive Bone-Cement Interfaces
Subchondral Bone Microarchitecture Changes in Animal Models of Arthritis
Microarchitectural Adaptations of Primary Osteoarthrotic Subchondral Bone
Ultrasonic Characterization of Dynamic Depth-Dependent Biomechanical Properties of Articular Cartilage
Mechanical Property of Trabecular Bone of the Femoral Heads from Osteoarthritis and Osteoporosis Patients.