Advances in Radiation Oncology in Lung Cancer
E-Book
Although decades of laboratory and clinical research have led to incremental improvement in treatment outcome, lung cancer remains one of the most deadly diseases. This volume is unique in being devoted solely to the radiation oncology of lung cancer, and will be of great value to all who are involved in the diagnosis and treatment of the disease. Both non-small cell and small cell lung cancer are considered in detail. Current state-of-the-art treatment strategies and novel approaches that promise further improvements in outcome are explained and evaluated, with the aid of high-quality illustrations. Treatment-related toxicity is discussed, and further individual chapters focus on topics such as quality of life studies, prognostic factors and pitfalls in the design and analysis of clinical trials.
1;Foreword;6 2;Preface;7 3;Contents;8 4;1 Pretreatment Considerations;11 4.1;1.1 Molecular Biology and Genetics of Lung Cancer;12 4.2;1.2 Angiogenesis and Lung Cancer;21 4.3;1.3 Contemporary Issues in Staging of Lung Cancer;39 5;2 Basic Treatment Considerations;53 5.1;2.1 Lung Cancer Surgery;54 5.2;2.2 Radiation Therapy;66 5.2.1;2.2.1 Radiobiology of Normal Lung Tissue and Lung Tumours;66 5.2.2;2.2.2 Radiation Time, Dose, and Fractionation in the Treatment of Lung Cancer;73 5.2.3;2.2.3 Treatment Planning and Conformal Radiotherapy;82 5.2.4;2.2.4 Target Volumes in Non-Small Cell Lung Cancer;101 5.2.5;2.2.5 Target Volumes in Small Cell Lung Cancer;115 5.2.6;2.2.6 Radioprotectors and Chemoprotectors in the Management of Lung Cancer;126 5.3;2.3 Lung Cancer Chemotherapy for Radiation Oncologists;138 5.4;2.4 Radiotherapy and Chemotherapy;158 6;3 Current Treatment Strategies in Non- Small Cell Lung Cancer;170 6.1;3.1 Early Stage in Non-Small Cell Lung Cancer;171 6.1.1;3.1.1 Radiotherapy in Early Stage Non-Small Cell Lung Cancer;171 6.1.2;3.1.2 Postoperative Radiotherapy for Non- Small Cell Lung Carcinoma;191 6.1.3;3.1.3 Photodynamic Therapy;201 6.2;3.2 Locally Advanced Non-Small Lung Cancer;208 6.2.1;3.2.1 Radiochemotherapy in Locally Advanced Non-Small Cell Lung Cancer;208 6.2.2;3.2.2 Chemotherapy or Chemoradiotherapy Followed by Surgical Resection for Non- Small Cell Lung Cancer;224 6.2.3;3.2.3 Palliative External Beam Thoracic Radiotherapy;248 6.2.4;3.2.4 Intraoperative Electron Beam Radiotherapy in Lung Cancer;256 6.2.5;3.2.5 Intraluminal Radiotherapy;270 7;4 Treatment of Small- Cell Lung Cancer;276 7.1;4.1 Limited-Disease of Small Cell Lung Cancer;277 7.2;4.2 Prophylactic Cranial Irradiation in Small Cell Lung Cancer;287 8;5 Radiation Therapy for Recurrent Lung Cancer;296 9;6 Radiotherapy for Lung Cancer in Elderly Patient;307 10;7 Advances in Supportive and Palliative Care for Lung Cancer Patients;319 11;8 Treatment-Related Toxicity;335 11.1;8.1 Hematologic Toxicity in Lung Cancer;336 11.2;8.2 Radiation-Induced Lung and Heart Toxicity;348 11.3;8.3 Spinal Cord;363 11.4;8.4 Radiation Therapy-Related Toxicity: Esophagus;369 11.5;8.5 Brain Toxicity;379 12;9 Quality of Life in Radiation Oncology of Lung Cancer;390 13;10 Prognostic Factors in Lung Cancer;405 14;11 Future Strategies in Lung Cancer;415 14.1;11.1 Intensity-Modulated Radiation Therapy for Lung Cancer;416 14.2;11.2 Stereotactic Radiotherapy and Gated Therapy;427 14.3;11.3 Novel Substances in the Treatment of Lung Cancer for the Radiation Oncologist;438 14.4;11.4 PET Scanning in Staging and Evaluation of Response to Treatment in Lung Cancer;452 14.5;11.5 Heavy Particles in Lung Cancer;463 14.6;11.6 Translational Research in Radiation Oncology of Lung Cancer;470 15;12 Pitfalls in the Design, Conduct and Analysis of Randomised Clinical Trials;483 16;13 New Directions in the Evaluation and Presentation of Clinical Research in Lung Cancer;492 17;Subject Index;500 18;List of Contributors;503
Jeremic, Branislav
| ISBN | 9783540266327 |
|---|---|
| Artikelnummer | 9783540266327 |
| Medientyp | E-Book - PDF |
| Copyrightjahr | 2005 |
| Verlag | Springer-Verlag |
| Umfang | 526 Seiten |
| Sprache | Englisch |
| Kopierschutz | Digitales Wasserzeichen |
