"Aged? But he does not appear aged, just look, his hair has remained young!" Marcel Proust, In Search of Lost Time (1913-27) The appearance of hair plays an important role in peoples' overall physical appe- ance and self-perception. With today's increasing life-expectation, the desire to look youthful plays a bigger role than ever. The hair care industry has become aware of this, and capable to deliver active products that are directed toward meeting this c- sumer demand. The discovery of pharmacological targets and the development of safe and effective drugs such as minoxidil and fnasteride also indicate strategies of the drug industry for maintenance of healthy and beautiful hair in the young and old. The study of hair aging focuses on two main streams of interest: On the one hand, the esthetic problem of aging hair and its management, in other words everything that happens outside the skin; on the other hand, the biological problem of aging hair, in terms of microscopic, biochemical, and molecular changes, in other words the "secret life" of the hair follicle in the depth of the skin. Hair aging comprises hair shaft aging, and aging of the hair follicle. The former involves weathering and photoaging of the hair shaft, while the latter manifests as decrease of melanocyte function (graying) and decrease in hair production (alopecia).

Gerontobiology of the Hair Follicle

Molecular Basis of Androgenetic Alopecia
Inflammatory Phenomena and Fibrosis in Androgenetic Alopecia
Post-Menopausal Frontal Fibrosing Alopecia
Female Pattern Hair Loss
Hair Growth Parameters in Pre- and Postmenopausal Women
Comparative Histopathology of Androgenetic Alopecia, Diffuse Alopecia, and Senescent Alopecia
Comparative Gene Expression Profiling of Senescent and Androgenetic Alopecia Using Microarray Analysis
The Aging Hair Pigmentary Unit
Oxidative Stress Associated Melanocyte-Loss and Hair Growth Capacity in the Aging Hair Follicle: A Model for Tissue-Specific Aging
Human Hair Follicle Melanocytes as a Proxy Cell Type in Neurodegeneration Research
Effect of UV Radiation on Scalp and Hair Growth
Hair Photoaging
Effect of Tobacco Smoking on Hair
Age-Related General Problems Affecting the Condition of Hair
Aging of Scalp and Age-Related Disorders of Scalp
Care of Aging Hair and Photoprotection
Possibilities and Limitations for Reversal of Age-Related Hair Loss
Possibilities and Limitations for Reversal of Age-Related Pigment Loss
Evidence-Based Hair Transplantation
Future Directions: Gene Polymorphism Diagnostics Relevant to Hair
Future Directions: The Known and Unknown Roles of Hair-Follicle Stem Cell Types
Future Directions: Bioengineering the Hair Follicle
Hair After Death.