1;Preface;6 2;Contents;8 3;Models and Algorithms;13 4;A Personalised Virtual Coach to Counteract Ageing Decline: The H2020 NESTORE Project;14 4.1;1 Introduction;15 4.2;2 The Wellbeing Dimensions of NESTORE;16 4.3;3 Scope of NESTORE and Key Innovations;17 4.4;4 The NESTORE Methodological Approach and Validation;18 4.5;5 Cost-Effectiveness and Sustainability of NESTORE;20 4.6;6 Conclusions;21 4.7;References;22 5;Multi-domain Model of Healthy Ageing: The Experience of the H2020 NESTORE Project;23 5.1;1 Introduction;24 5.2;2 NESTORE Model of Healthy Ageing;24 5.3;3 Physiological Status and Physical Activity Behaviour;25 5.4;4 Nutrition;27 5.5;5 Cognitive and Mental Status and Social Behaviour;27 5.6;6 NESTORE Healthy Ageing Model Outcomes;29 5.7;7 Conclusions;30 5.8;References;30 6;New Models in Managing Out-of-Hospital Care of Chronic Patients and Aging Population;32 6.1;1 Introduction;32 6.2;2 Integrated Out-of-Hospital Care Solutions;33 6.2.1;2.1 The Birth of the AICare Idea and the First Applications;34 6.2.2;2.2 Pilot Study Population;35 6.3;3 Aicare Marketplace: Improved Accessibility Putting the Patient at the Center of Care;35 6.3.1;3.1 The AICare Model;36 6.3.2;3.2 The AICare Platform in Brief;37 6.4;4 Involvement of Non-medical Professionals in the Care Program;40 6.5;5 Different Approaches: "Top-Down" in National Systems Versus "Bottom-Up" in Private Care Options;40 6.6;6 Collaboration Between Partner Companies/Hospitals;41 6.7;7 Working on All Aspects of Health-Not Only the Disease;41 6.8;8 Conclusions;41 6.9;References;42 7;From Ambient Assisted Living to Society Ambient Living;43 7.1;1 Introduction;43 7.2;2 From Tradition to Innovation;44 7.2.1;2.1 Generalization of the Assistive Technology Approach;46 7.2.2;2.2 Increasing Use of Intelligence;46 7.3;3 Technology Developments;49 7.3.1;3.1 Environments with Intelligent Objects;49 7.3.2;3.2 Intelligent Environments and Dedicated Networks;50 7.3.3;3.3 Extension to the Entire Society;51 7.4;4 Examples of Experimental Implementation;52 7.5;5 Conclusion;53 7.6;References;53 8;Designing Multidimensional Assessment of ICTs for Elderly People: The UNCAP Clinical Study Protocol;54 8.1;1 Background and Rationale;55 8.1.1;1.1 Aging of EU Population and Needs for Innovative Technologies;55 8.1.2;1.2 Evaluating Safety and Effect of Innovative Technologies;56 8.2;2 The UNCAP Bundle;57 8.2.1;2.1 System Architecture;57 8.2.2;2.2 Indication for Use;58 8.3;3 Available Evidences on ICTs for the Elderly with CI;59 8.4;4 Study Design;61 8.4.1;4.1 Objectives and Research Questions;62 8.4.2;4.2 Study Dimensions and Outcome Variables;62 8.4.3;4.3 Primary and Secondary Hypotheses and Study Endpoints;62 8.4.4;4.4 Criteria for Recruiting Participants;62 8.4.5;4.5 Recruitment Process;66 8.4.6;4.6 Sample Size;67 8.4.7;4.7 Control Groups for Primary End-Users (EP) and ICGs;69 8.4.8;4.8 Randomization Procedures;69 8.4.9;4.9 Criteria for Discontinuing Individuals;69 8.5;5 Study Procedure;70 8.5.1;5.1 T0 (Enrolment Time);70 8.5.2;5.2 T1 (UNCAP First Time Exposure for Test Groups. Training);71 8.5.3;5.3 T2 (Evaluation of UNCAP Acceptance and Starting of UNCAP Evaluation);72 8.5.4;5.4 T3 (Intermediate UNCAP Evaluation);72 8.5.5;5.5 T4 (End of the Evaluation Period);72 8.6;6 UNCAP Multidimensional Assessment;73 8.7;7 Conclusions;75 8.8;References;75 9;A Technological Approach to Support the Care Process of Older in Residential Facilities;77 9.1;1 Introduction;78 9.2;2 The OPENCARE Architecture;79 9.2.1;2.1 Air Quality Sensor;80 9.2.2;2.2 Bed Sensor;81 9.2.3;2.3 Data Introduced by Tablet Interface;81 9.3;3 Data Acquisition and Elaboration;82 9.4;4 Conclusion;84 9.5;References;84 10;A Non-invasive Method for Biological Age Estimation Using Frailty Phenotype Assessment;86 10.1;1 Introduction;86 10.2;2 Related Works;88 10.3;3 Method and Materials;90 10.3.1;3.1 Frailty Phenotype;91 10.3.2;3.2 Evaluation Protocol;92 10.3.3;3.3 Cloud Application;93 10.3.4;3.4 Biological Age Estimation;94 10.4;4 Results;95 10.5;