Amino Acids Biosynthesis presents the current knowledge of fundamental as well as applied microbiology of amino acids. Topics discussed are the amino acid biosynthetic pathways, their genetic and biochemical regulation, transport of amino acids and genomics of producing microorganisms. The characterization of the control mechanisms of amino acid biosynthesis has revealed insights into principles of genetic and biochemical regulation, such as transcriptional regulators and a new class of regulatory elements, the riboswitch.

The volume further deals with the metabolic engineering of microorganisms for the biotechnological production of amino acids for use as pharmaceuticals and, particularly, as food and feed additives. Comprehensive reviews are given of recent achievements to enable or improve production of amino acids and dipeptides by fermentation and enzyme catalysis. Here, the particular focus is on metabolic engineering, the rational improvement of metabolic functions using recombinant DNA technology.

Production of Glutamate and Glutamate-Related Amino Acids: Molecular Mechanism Analysis and Metabolic Engineering

The l-Lysine Story: From Metabolic Pathways to Industrial Production
l-Threonine
Aromatic Amino Acids
Branched-Chain Amino Acids
Methionine Biosynthesis in Escherichia coli and Corynebacterium glutamicum
Cysteine Metabolism and Its Regulation in Bacteria
Microbial Arginine Biosynthesis: Pathway, Regulation and Industrial Production
l-Serine and Glycine
Alanine, Aspartate, and Asparagine Metabolism in Microorganisms
Amino Acid Transport Systems in Biotechnologically Relevant Bacteria
Occurrence, Biosynthesis, and Biotechnological Production of Dipeptides
Genomes and Genome-Level Engineering of Amino Acid-Producing Bacteria.