The Annual Update compiles reviews of the most recent developments in clinical intensive care and emergency medicine research and practice in one comprehensive book. The chapters are written by well recognized experts in these fields. The book is addressed to everyone involved in intensive care and emergency medicine, anesthesia, surgery, internal medicine, and pediatrics.

Sepsis and the Immune Response

The role of mitochondria in the immune response in critical illness
Immunomodulation by tetracyclines in the critically ill: an emerging treatment option?
Hit early: blocking interleukin-1 in the treatment of COVID-19 pneumonia
Hemoadsorption therapy during ECMO: emerging evidence
Respiratory Issues
The forgotten circulation and transpulmonary pressure gradients
Oxygen: origin, pathophysiology, and use in the critically ill
Nebulized therapeutics for COVID-19 pneumonia in critical care
Mechanical Ventilation
Positive end-expiratory pressure in invasive and non-invasive ventilation of COVID-19 ARDS
Personalized mechanical ventilation setting: slow is better!
Spontaneous breathing in acute respiratory failure
Laryngeal injury: impact on patients in the acute and chronic phases
Fluids and Electrolytes
Fluid responsiveness as a physiologic endpoint to improve successful weaning
Tidal volume challenge test: expanding possibilities
Fluid management in COVID-19 ICU patients
Electrolytes in the ICU
Renal Failure
Hemodynamic alterations during continuous renal replacement therapy: is it all about fluid?
How to prolong filter life during continuous renal replacement therapy?
Prevention of acute kidney injury after cardiac surgery
Circulatory Shock
Contrast enhanced renal ultrasound: an emerging technique for assessment of renal perfusion in critically ill patients
Focused clinical hemodynamic assessment in septic shock
Vasopressor choice and timing in vasodilatory shock
Cardiac arrest
Advanced life support update
Brain injury biomarkers for predicting outcome after cardiac arrest
Neurocritical care and Neuromonitoring
The emerging role of the microbiota in neurocritical care
Brain-multiorgan cross-talk in critically ill patients with acute brain injury
The importance of neuromonitoring in non-brain injured patients
Artificial intelligence
Artificial intelligence in critical care medicine
Artificial intelligence in infection management in the ICU
Quality of care
Acute medical rehabilitation in intensive care
Sepsis performance improvement programs: from evidence towards clinical implementation.