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This book reviews the development, characterization and applications of aptamers in different areas of biotechnology ranging from therapeutics to diagnostics and protein purification. Hailed as chemical antibodies, these single-stranded nucleic acid receptors were predicted to supersede antibodies in traditional assays, such as ELISA, within a short time. While this has yet to happen, readers will find in this book a deep insight into the progress of aptamer technology and a critical discussion about the limitations that need to be overcome in order to find wider acceptance and use outside of the still relatively small aptamer-community.

This book covers all aspects of aptamer generation and application for the aptamer-experienced reader and curious novice alike, with the addition of an industry perspective on the future of aptamer-use in biotechnology. 




Biophysical Characterization of Aptamer-Target Interactions
Impedimetric Aptamer-based Biosensors: Principles and Techniques
Impedimetric Aptamer-based Biosensors: Applications
Aptamer-based affinity chromatography for protein extraction and purification
Aptamers in diagnostic and molecular imaging applications
Aptamer-modified nanoparticles in medical applications
Defining Target Product Profiles (TPPs) for Aptamer based diagnostics.
ISBN 978-3-030-54063-0
Artikelnummer 9783030540630
Medientyp Buch
Auflage 1st ed. 2020
Copyrightjahr 2021
Verlag Springer, Berlin
Umfang VII, 215 Seiten
Abbildungen VII, 215 p. 61 illus., 47 illus. in color.
Sprache Englisch