Clinical studies during the past 10 years have shown that PET is more sensitive than CT and MRI for the detection of many tumors. In many cases, however, for example in head and neck tumors, combination with radiological procedures is necessary. It may be speculated that PET should be the first study in a malignant tumor when metastatic spread is suspected. MRI and CT may then be restricted to those body areas which evince sites of increased glucose metabolism. Thus, a combination of metabolic and morphologic procedures will enhance tumor detection and change the therapeutic strategy. In this light, an atlas including PET, CT, MRI, and histology data seems desirable to combine metabolic and morphologic imaging. This book presents an overview of the available data which should be of great interest not only for specialists in radiology and nuclear medicine, but also for oncologists.

1 Introduction

2 Principles of Positron Emission Tomography
2.1 F-18 Fluorodeoxyglucose(FDG)
2.2 Principles of Measurement
References
3 Normal Findings
3.1 Technique
3.2 Qualitative Image Assessment
4 Cancer of the Head and Neck
4.1 Primary Tumor
4.2 Lymph Node Metastases
4.3 Recurrence
4.4 Distant Metastases
4.5 Pitfalls
5 Malignant Melanoma
5.1 In Transit and Limited Nodal Metastases (AJCC Stage III)
5.2 Distant metastases (AJCC Stage IV)
5.3 Pitfalls
References
6 Colorectal Cancer
6.1 Sensitivity and Specificity of PET vs. CT
6.2 Preoperative Staging of Recurrent Tumor
6.3 Diagnosis of Recurrent Tumor
6.4 Preoperative Staging of Primary Tumor
6.5 Indications for PET Imaging
6.6 Technical Issues
References
7 Thyroid Cancer
7.1 Primary Tumor/Preoperative Staging
7.2 Differentiated Thyroid Cancer
7.3 Medullary Thyroid Cancer
References
8 Non-Small Cell Lung Cancer
8.1 PET Imaging Protocols Used in This Chapter
8.2 Primary Tumor
8.3 Local Recurrence
8.4 Lymph Node Metastases
8.5 Distant Metastases
8.6 Variants and Pitfalls
9 Breast Cancer
9.1 Primary Tumor
9.2 Local Recurrence
9.3 Axillary Lymph Node Metastases
9.4 Distant Metastases
10 Testicular Germ Cell Tumors
11 Malignant Lymphomas
11.1 Nodal Disease
11.2 Extranodal Disease
11.3 Lymphoma Relapse
11.4 Therapy Control
11.5 Variants and Pitfalls
12 Pancreatic Lesions
12.1 Ductal Adenocarcinoma
12.2 Other Malignant Tumors
12.3 Metastases
12.4 Chronic Pancreatitis
12.5 Pitfalls
References
13 Brain Tumors
13.1 PET Imaging Protocol Used in This Chapter
13.2 Primary Tumor: High Grade
13.3 Primary Tumor: Low Grade
13.4 Primary Tumor: Others
13.5 Intracranial Metastases
References
14 GynecologicalTumors (Except Breast Cancer).