This volume contains 10 chapters. The contributions are from researchers - mousintheirrespective?eldsandthechapterscontainhighqualityreviewson topics related to the chemo-biologicalstudies of several different heterocyclic groups. The ?rst chapter from Saracoglu reviews the functionalization of indoles andthepyrrolesviaMichaeladditions,asthesecompoundshavepotential for their biologicalactivities. InsecondchapterMen endezreviewsthechemistryofthewelwitindolinones. Topcu and Demirkiran, in the third chapter, describe the chemistry and biological studies of lignans from Taxus species, including their biosynthesis andrecent strategiesforthesynthesisoflignans.Lignansareaveryimportant classofmolecules,astheyhaveaverydiversespectrumofbiologicalactivities, such as antitumour, antiviral, hepatoprotective, antioxidant, antiulcer, an- allergen, anti-platelet, and anti-osteoporoticactivities. InnextchapterSuzen describestheantioxidantactivitiesofsyntheticindole derivatives and their possible mechanisms of action. Inchapter?veGonz alezetal.presentsacomprehensivereviewonthech- istry and biology of the quinoxaline 1,4-dioxide and phenazine 5,10-dioxide typemolecules.Theyalsodiscussthemodeofaction,structure-activitystudies andother relevant chemical andbiologicalproperties forsuch molecules. Inthechaptersix,Khanbrie?ydiscussestheanti-angiogenicandtelomerase inhibitory activities of quinoline and its analogues. Liuet al.,inchapterseven, brie?y reviewssomeaspects ofstudies ofbio- tive marine sponge furanosesterterpenoids from the last 10 years, including their totalsyntheses. Pujol et al. in chapter eight, reviews the chemistry, origin and antiviral activities of naturally occurring sulfated polysaccharides for the prevention and controlof viral infections such as HIV-1 and -2, human cytomegalovirus (HCMV), dengue virus (DENV), respiratory syncytial virus (RSV), and - ?uenza Avirus. InchapternineHamdietal.describesthesynthesisandbiologicalactivities of the heterocyclicand vanillin ether coumarins. In the last chapter, Orhan et al. reviews their recent ?ndings on antiviral and antimicrobial heterocyclic compounds fromTurkish plants. Tromsø,Norway 2007 Mahmud Tareq Hassan Khan Contents FunctionalizationofIndoleandPyrroleCores viaMichael-TypeAdditions N.Saracoglu ................................ 1 ChemistryoftheWelwitindolinones J.C.Menéndez ............................... 63 LignansFrom TaxusSpecies G.Topcu·O.Demirkiran.......................... 103 AntioxidantActivities ofSyntheticIndoleDerivatives andPossibleActivity Mechanisms S.Süzen................................... 145 Quinoxaline 1,4-DioxideandPhenazine5,10-Dioxide.

Functionalization of Indole and Pyrrole Cores via Michael-Type Additions

Chemistry of the Welwitindolinones
Lignans From Taxus Species
Antioxidant Activities of Synthetic Indole Derivatives and Possible Activity Mechanisms
Quinoxaline 1,4-Dioxide and Phenazine 5,10-Dioxide. Chemistry and Biology
Quinoline Analogs as Antiangiogenic Agents and Telomerase Inhibitors
Bioactive Furanosesterterpenoids from Marine Sponges
Natural Sulfated Polysaccharides for the Prevention and Control of Viral Infections
4-Hydroxy Coumarine: a Versatile Reagent for the Synthesis of Heterocyclic and Vanillin Ether Coumarins with Biological Activities
Antiviral and Antimicrobial Evaluation of Some Heterocyclic Compounds from Turkish Plants.