Bioactive Spin Labels

Bioactive Spin Labels

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Bioactive Spin Labels focusses on nitroxyl radicals, their chemistry, biological activity and their application as paramagnetic contrast agents in biomedical research. New EPR techniques for in-vivo studies utilizing nitroxyl radical reagents are described. Recent results on stable nitroxyl radicals as anticancer, antishock, antiaggregant and antischemic drugs are summarized.

Spin-Labeled Medicines: Enzymes, Biomembranes and Possible Pharmaceuticals. An Overview
Nitroxyl Radicals and Non-Radical Reactions of Free Radicals
Triacetonamine in the Chemistry of Nitroxyl Radicals
Catalysis of Redox Processes by Nitroxyl Radicals
Biomembrane Reactions of Nitroxyl Radicals
Relaxation Processes Involving Nitroxyl Radicals in Molecular Biology
Investigations on Spin Exchange in Nitroxyls by the Method of Continuous Saturation of EPR Spectra
Spin Exchange Components in Nitroxyl Biradicals EPR Spectra
Investigation of Spin Labels and Probes by Millimeter Band EPR
Analysis of Spin Label Slow Motions Based on Simulating 2-mm Band EPR Spectra
Synthesis and Properties of Spin-Labeled Phospholipids
Spin-Labeled Phospholipids for Protein-Lipid Interactions
Spin-Labeled Organophosphorus Compounds
Spin-Labeled Close Analogs of Sugars and Nucleosides
Spin-Labeling Study of the Structure and Function of Leucine Aminopeptidae
Photoaffinity Spin Labeling
The Toxicity of Aminoxyl Radicals
Nitroxyl Radicals for Cancer Chemotherapy
Spin Labeling Study of Platelet Plasma Membrane and Nitroxyl Aggregation Inhibitors
Anti-Ischemic Effect of 1-Hydroxy Derivatives of Nitroxyl Bioantioxidants
Spin Probes for the Study of Intact and Cancer Cell Membranes
Pharmacokinetics of Nitroxyl Radicals
Computer-Assisted Evaluation of Nitroxyl Radical Effect on Biological Activity
Aminoxyl Radicals as MRI Contrast Agents
Aminoxyl Spin Labels in Clinical Analysis
Applications of Spin-Label Techniques at High Pressures.
ISBN 978-3-642-48726-2
Artikelnummer 9783642487262
Medientyp Buch
Auflage Softcover reprint of the original 1st ed. 1992
Copyrightjahr 2012
Verlag Springer, Berlin
Umfang X, 636 Seiten
Abbildungen X, 636 p. 48 illus.
Sprache Englisch