This book provides a comprehensive and complete overview of biomarkers in clinical practice for inflammatory bowel disease (IBD) bringing together the literature in a clear and concise manner. The book bridges the gap between growing knowledge at the bench and current and future applications of biomarkers in clinical practice. 

The central structure of the book focuses on prognostic and predictive biomarkers in IBD with an emphasis on the fields of research and scientific techniques (genomics, proteomics and metabonomics) that have led to biomarker discovery and places these biomarkers within a clinical context to help understand their utility in clinical practice.

This book will be of use to clinicians who have an interest in using biomarkers in clinical practice as well as clinician researchers and scientists involved in the biomarker research pipeline.

The author team comprises experts from around the world in order to bring together the literature in an effort to inform clinicians and researchers about the current state-of-the art in biomarker discovery.  It is intended to  assist future research efforts and indicate how biomarkers might be best applied to clinical practice both at present and in the future.

Part I: Introduction

nflammatory bowel disease - more than meets the eye - Clinical risk factors - lessons from epidemiology
Clinical trial design for biomarker discovery
Database/ big data meets real world
Patient reported outcomes.- Part II: Biomarkers - Prognostic vs Predictive.- Biomarkers for remote monitoring.- Disease modification.- Part IIV: Crohn's disease.- Luminal Crohn's disease-. Perianal CD.- Fibrosis/ strictures in CD.- Post-op Crohn's disease.- Part IV: Ulcerative colitis
UC surveillance
Acute severe UC
Chronic active UC
Pouchitis
Refractory proctitis
Feacal microbiota transplantation
Primary sclerosing cholangitis
Extraintestinal manifestations of IBD.- Part V: Specialised scenarios
Pregnancy
Nutrition
TDM
Biomarkers to quantify immune response
Drug toxicity.- Part VI:Scientific
Exposome and diet
Microbiota
Metabonomics
Immunology
Genomics
Systems Biology in Biomarker research
Part VII: Ideal tools for investigation in the future.