Bipolar disorder is a common, complex and costly mental health disorder, which sits at the heart of the practice of clinical psychiatry.

Effective treatments (pharmacological, psychological and brain stimulation based) have all been discovered serendipitously.  

With the huge advances in basic neuroscience the way is now clear for novel treatments to be developed based on brain science. This book reviews these possibilities.

Preface

The Neurobiology of Bipolar Disorder
Pre-clinical studies and Animal Models
Genetics in Bipolar.- <b>Mitochondrial modulators for bipolar disorder: A paradigm for drug development</b>
Intracellular Signaling Cascades
Circadian Rhythms and Sleep
Neuroendocrine System in Bipolar
Neuroanatomic and Functional Neuroimaging Findings
Structural and Functional Aspects of Neuroprogression in BD
Inflammation as a Mechanism of Neuroprogression
Neurocognition in Bipolar
The kindling/sensitization model and Early Life Stress.-  Early Life Stress in Bipolar
New pharmacological Interventions.