In a rapidly progressing field, Botulinum Toxin Therapy provides both clinicians and basic researchers with the latest science on the structure and function of botulinum toxins and the use of these toxins to treat a wide variety of diseases. Part 1 of the book reviews the basic science of botulinum toxins including advances in our understanding of  the molecular structure and mechanism of action of botulinum toxins. This section also discusses the manufacturing and formulation of botulinum toxins for clinical use and the development of novel therapeutic toxins for the future. Part 2 reviews the use of botulinum toxins in clinical practice. It discusses the clinical pharmacology of botulinum toxin drugs and their use in a wide variety of clinical conditions including headache, spasticity, pain, disorders of the genitourinary and gastrointestinal tract, strabismus, and medical aesthetics.

Part 1. Basic Science.-  The History of Botulinum Toxins in Medicine: A Thousand Year Journey

The History of Botulinum Toxins in Medicine: A Thousand Year Journey
Botulinum Neurotoxins: Mechanism of Action
Manufacturing and Clinical Formulations of Botulinum Neurotoxins
Novel Native and Engineered Botulinum Neurotoxins
Part 2. Clinical Practice
Clinical Pharmacology of Botulinum Toxin Drugs
The Use of Botulinum Toxin for Treatment of the Dystonias
The Use of Botulinum Toxin for Treatment of Spasticity
Use of Botulinum Toxin in Ophthalmology
Hyperhidrosis and Aesthetics
Use of Botulinum Toxin in Genitourinary System
Gastrointestinal Uses of Botulinum Toxin
The Use of Botulinum Toxin in the Management of Headache Disorders
Botulinum Toxin and Pain
The Use of Botulinum Toxin for Treatment of Depression.