The minimally invasive use of botulinum toxins (BoNT) in the lower urinary tract has transformed the treatment of difficult bladder, urethra, and prostate conditions refractory to conventional therapy. This is the first book on the practical application of BoNT to the genitourinary tract. After discussion of the biology and pharmacology of BoNT, applications of BoNT in the bladder and the prostate and pelvic floor are discussed in detail, with reviews of the latest clinical series and techniques of BoNT injection. The book also considers non-genitourinary uses of BoNT and issues of health economics. The editor-in-chief, Dr. Michael Chancellor, was an early pioneer of BoNT use in North America and was the first to undertake comprehensive basic research into BoNT in the urinary tract. The contributing authors are leading authorities from across the world. This book will be of interest to all urologists and urogynecologists who are considering the use of BoNT in their practice.

Anatomy, physiology and pathophysiology of the GU tract

Biology and clinical pharmacology of btx
Bladder: Neurogenic bladder. IOAB. Painful bladder syndrome. Interstitial cystitis
Prostate and pelvic floor: BPH. Prostatitis. DSD. Genital-pelvic floor disorders
Non-genitourinary uses of BoNT: Health economics and comparative efficacy.