This volume highlights the remarkable new developments in brain imaging, including those that apply magnetic resonance imaging (MRI) and Positron Emission Tomography (PET), that allow us to non invasively study the living human brain in health and in disease. These technological advances have allowed us to obtain new and powerful insights into the structure and function of the healthy brain as it develops across the life cycle, as well as the molecular make up of brain systems and circuits as they develop and change with age. New brain imaging technologies have also given us new insights into the causes of many common brain disorders, including ADHD, schizophrenia, depression and Alzheimer's disease, which collectively affect a large segment of the population. These new insights have major implications for understanding and treating these brain disorders, and are providing clinicians with the first ever set of biomarkers that can be used to guide diagnosis and monitor treatment effects. The advances in brain imaging over the last 20 years, summarized in this volume, represent a major advance in modern biomedical sciences.

From the contents

Preface
Food and drug reward: overlapping circuits in human obesity and addiction
Nonhuman Primate Models of Addiction and PET Imaging: Dopamine System Dysregulation
Neural and behavioral endophenotypes in ADHD
Experimental protocols for behavioral imaging: Seeing animal models of drug abuse in a new light
Molecular Imaging and the Neuropathologies of Parkinson's disease
Imaging of Seasonal Affective Disorder and Seasonality effects on serotonin and dopamine function in the Human Brain
Magnetic resonance spectroscopic methods for the assessment of metabolic functions in the diseased brain
MR Spectroscopic Studies of the Brain in Psychiatric Disorders
fMRI As A Measure of Cognition Related Brain Circuitry In Schizophrenia
MRI studies in Late-Life Mood Disorders
The role of diffusion tensor imaging in the study of cognitive aging
Structural, functional and spectroscopic MRI studies of Methamphetamine addiction
Pharmacological MRI Approaches to Understanding Mechanisms of Drug Action.