In mammals, a robust physiologic system acts to maintain relative constancy of weight. A key element of this system is leptin. The nature of this "brain-somatic" cross talk is as yet poorly understood, but it is likely to have important implications for the pathophysiology and treatment of obesity, diabetes and other metabolic disorders.  

Interactions of Growth Hormone Secretagogues with Leptin-Sensitive Brain Networks

Leptin and the Neural Circuit Regulating body Weight and Metabolism
Role of the Growth Hormone Secretagogue Receptor in the Central Nervous System
Regulation of Galanin-Like Peptide (GALP) in the Brain and Posterior Pituitary: A Review
Ghrelin and the Growth Hormone Neuroendocrine Axis
Adipose Tissues as Part of the Immune System: Role of Leptin and Cytokines
Regulation of Body Weight Homeostasis During Pregnancy and Lactation
Ghrelin: From GH Control to Feeding Behaviour and Sleep Regulatio
Effect of Leptin on Fatless Mice
Leptin, Growth and Reproduction
An Emerging Role of Leptin in Clinical Psychiatry
Genomic approach to common human obesity
The Epigenetic Inheritance Hypothesis.