Important contributions about the treatment modalities of breast cancer are presented in this book. The risks and limitations of breast conserving therapy of mammary carcinoma are dealt with. Newest findings show that this form of therapy has the same outcome as conservative treatment modalities. The book also considers controversial issues such as the treatment of mastopathy, precancerous, and non-invasive lesions of the breast. New, but not yet approved, regimes for the prevention of mammary carcinoma and open questions concerning adequate operative treatment are discussed. Latest results presented here show that all modern palliative chemotherapy has a certain but limited effect on outcome and that early detection and preventive therapy (surgical and hormonal) will be of great importance for improved chances of survival of breast cancer.

I. Biology, Morphology, Growth Behavior

Epidemiology of Breast Cancer
Breast-Cancer Biology and Breast-Preserving Surgery
S Phase Fractions and DNA Ploidy as Prognostic Factors in Breast Cancer
Multicentricity in Breast Carcinoma
The Contralateral Breast: Bilateral Primary Breast Cancer
Cell Biology of Tumor Metastasis Formation
Prognostic Factors in Primary Breast Cancer
Natural Growth Rate of Primary Breast Cancer and its Metastases
Growth Rates and Cytokinetic Behavior of Breast Cancer
II. Diagnosis
The Value of Diagnostic Methods: Mammography, Screening and Other Imaging Techniques
Standards in the Technique of Mammography
Current Status of Ultrasound Mammography
Cytologic Diagnosis of Breast Cancer
III. Primary Treatment
Growth Behavior and Implications for Staging and Therapy
Rationale for the Choice of Treatment
Perioperative Clarification of Diagnosis
Surgical Treatment
Breast-Conserving Therapy or Amputation with Reconstruction: The Patient's View
Surgical Techniques of Breast Preservation for Early Breast Cancer
Conservation Trials in Early Breast Cancer
Surgical Complications After Conservative Treatment of Breast Cancer
IV. Radiology
Status of Radiotherapy after Ablative and Breast-Preserving Treatment of Breast Cancer
Treatment of Breast Cancer with Breast Preservation
First Experiences in Wurzburg of Interstitial Low-Dose Afterloading for Breast-Conserving Therapy with the Microselectron
V. Results
Long-Term Survival Following Breast-Conserving Therapy in Comparison to Radical Surgical Treatment: An Overview
Breast-Conserving Treatment: Experience Derived from the National Surgical Adjuvant Breast Project
Local Recurrence After Breast-Conserving Treatment: Results from the Harvard Joint Centerfor Radiation Therapy
Local Recurrence and New Primary Ipsilateral Carcinomas After Conservative Treatment of Breast Carcinoma
Pathoanatomical Characteristics of Local Treatment Failure Following Breast-Conserving Therapy
Selective Issues in the Evaluation of the Efficacy of Breast-Conserving Therapy
VI. Complications
Long-Term Complications of Surgery and Associated Irradiation as Breast-Conserving Therapy
Long-Term Complications of Breast-Conserving Treatment: Experience with the Basel Lumpectomy Protocol
The German Breast Cancer Study I: Preliminary Results of Breast-Conserving Treatment Dependent on Radiation Technique
Long-Term Results and Late Complications After Breast-Preserving Therapy of Breast Cancer in Vienna
Possible Risk of Second Primary Cancers Associated with Irradiation in Breast-Conserving Therapy
Psychological Problems of Women with Carcinoma of the Breast and Possible Means of Treatment
Side Effects and Major Complications of Breast-Conserving Therapy
Cosmetic Aspects of Breast-Conserving Therapy for Carcinoma of the Breast
VII. Adjuvant Chemotherapy and Hormonal Therapy - Results and Complications
The Integration of Radiotherapy and Chemotherapy in the Treatment of Early Breast Cancer
Adjuvant Endocrine Treatment With and Without Simultaneous Adjuvant Chemotherapy
Complication Rates of Radiotherapy with Adjuvant Chemotherapy for Conservative Treatment
VIII. Strategies for the Prevention of Invasive Breast Cancer: Treatment of Mastopathic, Precancerous and Non-Invasive Lesions
Diagnosis and Classification of Benign Breast Diseases
Fibrocystic Disease, Precancerous Lesions, and Carcinoma In Situ: Characteristic Morphology and Risk of Malignant Degeneration
Multicentricity of Ductal Carcinoma In Situ.-Precancerous Lesions and Carcinoma In Situ: Problems of Treatment from the Morphological Viewpoint
Endocrinological Profiles in Benign Breast Disease
Endocrinology of Benign Breast Disease in Relation to the Severity of Radiological Dysplasia
Hormonal and Non-Hormonal Medical Therapy of Benign Breast Disease
Medical Treatment of Benign Breast Disease
In Situ Carcinoma of the Female Breast: Frequency, Growth Pattern and Biologic Significance
DNA Synthesis Rate and Ploidy in Precancerous and Non-Invasive Lesions of the Breast
Pathoanatomical Findings in Subcutaneous Mastectomy Specimens Referred to the Indications for Surgery.