This book provides healthcare professionals in Critical Care setting an easy consultation guide to fight against COVID-19. The book is divided into sections: Fundamentals of COVID-19, Pneumological critical care, Neurological manifestations, Cardiovascular manifestations, Renal manifestations, Haemostasis and coagulation, Other multi-organs involvement, Principles of therapy. 

Each section includes:

·         brief pathophysiology of COVID-19 (ventilation, neurological, cardiovascular, etc.);

·         principles of management (enriched with flowcharts and figures);

·         principles of therapy;

·         tips and key messages. 

Readers can find the most updated advices on how to face the ongoing pandemic: from principles of conventional oxygen therapy, assisted and invasive mechanical ventilation in critically ill COVID-19 patients to the complications sometimes underestimated. Tables and flowcharts provided are based on current knowledge in COVID-19 to help the clinician managing COVID-19 patients by a multiple-organs prospective.

Written by international key opinion leaders of each field, the book represents a point of reference for all professionals involved in the management of COVID-19 pandemic.

Part I. Fundamentals of COVID-19

Introduction and Essential multi-organs pathophysiology
Part II. Pneumological critical care of COVID-19
Pathophysiology and phenotypes
Radiological patterns and lung ultrasound
Noninvasive mechanical ventilation and conventional oxygen therapy
Criteria for intubation and ICU admission
Invasive mechanical ventilation
Weaning, tracheostomy and chest physiotherapy
Part III. Neurological manifestations of COVID-19
Brief pathophysiology
Clinical characteristics
Role of noninvasive neuro-monitoring systems and imaging
Biomarkers
Management of neurological complications
Part IV. Cardiovascular manifestations of COVID-19
Brief pathophysiology
Echocardiography, electrocardiogram and biomarkers
Clinical characteristics
Management
Part V. Renal manifestations of COVID-19
Brief pathophysiology
Clinical features and biomarkers
Renal replacement therapy
Part VI. Haemostasis and coagulation in COVID-19
Brief pathophysiology
Coagulation disorders and management
Part VII. Other multi-organs involvement (MODS-CoV-2)
Gastrointestinal manifestations (including hepatic disease)
Nutritional therapy
Part VIII. Principles of therapy
Sedation, analgesia, myorelaxants
Antibiotics, antiretroviral, corticosteroids, other therapies against SARS-CoV-2
Coagulation and haemostasis
Rescue therapies
Part IX. Appendix - Practical Aspects (Figures and Flowcharts).