This volume contains the main proceedings of the fourth international conference on "Cancer Prevention 2006," which was held during February 16-18, 2006, in St. Gallen, Switzerland. Written by international experts in the field, the book comprises a comprehensive update on the most recent developments in the upsurging fields of molecular biology and cancer genetics and their interactions with clinical epidemiology and cancer prevention at various levels: genetic/biologic predisposition and definition of high-risk groups; preclinical models and tumor prevention; prospects of surrogate endpoints and biomarkers; progress in imaging and detection of neoplastic precursor lesions; problems with Cox-2 inhibitors in tumor chemoprevention; primary and secondary prevention of gynecological, breast, gastrointestinal and genitourinary cancers. In addition, the future prospects of cancer chemoprevention are discussed.

Genetic Risk Profiles and Biomarkers in Cancer Prevention

A Favorable View: Progress in Cancer Prevention and Screening
Genetic Risk Profiles for Cancer Susceptibility and Therapy Response
Tumor Promotion as a Target of Cancer Prevention
Insulin-Like Growth Factor-Related Signaling and Cancer Development
Inflammation, Infection, and Cancer Prevention
Cytokines Are a Therapeutic Target for the Prevention of Inflammation-Induced Cancers
Prevention of Hepatocellular Carcinoma in Chronic Viral Hepatitis Patients with Cirrhosis by Carotenoid Mixture
Cox-2 and Cancer Chemoprevention: Picking up the Pieces
Prevention of Female and Male Genital Cancers
Human Papillomavirus Vaccine: A New Chance to Prevent Cervical Cancer
Prevention and Early Detection of Ovarian Cancer: Mission Impossible?
Prevention of Prostate Cancer: More Questions than Data
Prevention of Breast Cancer
Primary Prevention of Breast Cancer by Hormone-Induced Differentiation
The Genomic Signature of Breast Cancer Prevention
Estrogen Deprivation for Breast Cancer Prevention
Prevention of Colorectal Cancers
Primary Dietary Prevention: Is the Fiber Story Over?
Prevention and Early Detection of Colorectal Cancer - New Horizons
Prevention of Skin and Brain Tumors
New Perspectives on Melanoma Pathogenesis and Chemoprevention
Vitamin D - An Emerging Issue in Skin Cancer Control. Implications for Public Health Practice Based on the Australian Experience
Are Gliomas Preventable?
The Future of Cancer (Chemo)Prevention
Angiogenesis and Cancer Prevention: A Vision
An Estimate of Cancer Mortality Rate Reductions in Europe and the US with 1,000 IU of Oral Vitamin D Per Day
Uncovering Novel Targets for Cancer Chemoprevention
Conclusions and Summary
ConferenceSummary.