In about 5% of all organ (kidney, liver) transplant recipients, malignancies occur as a late complication of the massive immunosuppression. The malignancies are mainly skin cancers, lymphomas and renal carcinomas. The present book discusses the possible mechanisms of this type of tumorigenesis and inquires into possibilities of prevention. In particular, the described malignancies might be of viral origin. The book informs about a completely new type of carcinogenesis. Apart from the scientific aspects, it is of great practical value.

I De Novo Cancer in Organ Transplant Patients

Animal Models of Cancer Caused by Immunosuppression
Malignancies in Man After Organ Transplantation
Malignant Lymphoproliferation of Viral Origin in Transplant Patients
Clonality of Post-transplant Lymphoproliferative Diseases
Post-transplant Kidney Cancers and Skin Cancers (Including Kaposi's Sarcoma)
Discussion
II Treatment of Cancer by Organ Transplantation
Liver Transplantation for Malignant Disease
Bone Marrow Transplantation
Transplantation of the Upper Gastrointestinal Organs in Malignant Diseases
Discussion
III Possible Causes of Cancer in Transplant Patients
The Nordic Project on Renal Transplantation and Cancer
Human Papillomaviruses
Immune Response Directed Against Epstein-Barr Virus Carrier B Lymphocytes
Carcinogenic Effects of Immunosuppressive Drugs in Man
Influence of Blood Transfusions and Immunosuppressive Therapy on Malignancies in Renal Transplant Recipients
Possible Causes of Cancer in Transplant Patients
Discussion
IV Possible Prevention of De Novo Cancer in Transplant Patients
Post-transplant Malignancies: Clinical Preventive Measures
Immunologic Measures: Unresponsiveness or Tolerance
New Immunosuppressive Drugs
Cancer Related to Organ Transplantation: Summary and Conclusions
Discussion.