The purpose of this book is threefold: (1) review, and I realized that the script had to present a short but comprehensive survey spontaneously taken on the size and format of the localization of a number of transmit of a book. I wrote a letter to Mr. B. Lewer ich, of Springer-Verlag, advising him that ters and other neuroactive principles in the mammalian central nervous system, (2) to there would be some delay in the production provide some comments on the relation be of the third edition of The Human Central tween "classical" neuroanatomy and "chem Nervous System, that I happened to have gen ical" neuroanatomy, and (3) to suggest that erated an entirely different book on a brand by a synthesis of these two approaches of knowledge usually referred to as 'chemical "new" entities in the brain can, be delin neuroanatomy', and that I should like to eated. publish this work, as previous ones, with of the origin of this volume is Springer. Mr. Lewerich's reply was quite The history somwhat unusual and may be worth relating. characteristic: 'I must admit that, in spite In a previous book, namely Nieuwenhuys, of seven years of cooperation, you still suc Voogd and Van Huijzen: The Human Central ceed in surprising me; I had not the slightest Nervous System (second editi9n, 1981), there idea about your plans so far.

1 Introduction

2 Plan and Program
3 Survey of Chemically Defined Cell Groups and Pathways
Acetylcholine
Monoamines
Amino Acids
Gut-Brain Peptides
Hypophysiotropic Peptides
Neurohypophyseal Peptides
Pro-Opiomelanocortin Derivatives
Enkephalins
Dynorphins
Angiotensin II
4 Conclusions and Comments
5 'New' Entities in the Central Nervous System: The [Paracrine?] Core and Its Adjuncts
6 Classical Neuroanatomy, 'Chemical' Neuroanatomy and Neurobiology: Some Concluding Remarks
References.