The International Union Against Can knowledge of what to do or how to do it; cer convened a Conference on the to identify the nature of, and reason for, Chemotherapy of Choriocarcinoma in the successful chemotherapeutic results in Baguio City, Philippines to focus atten trophoblastic neoplasia (whether this be tion on the therapy of neoplasms of the specificity of drugs, the nature of the trophoblast. allogenic graft or characteristics of the Cures of cancer are of concern to every specific cells); and to determine the cau man. The oldest therapy of cancer likely ses for failures (whether it be advanced consisted of herbs, potions and incanta and long-standing disease, inappropriate tions. Cures may first have been achieved dosage regimens, or inherent resistance of in the murky annals of early civilization the tumors treated). If this first chemo with local chemical cautery. The first therapeutically curable cancer can serve successes of surgery are lost in antiquity as a model for the chemotherapy of other and probably were amputations. Radia autochthonous tumors, the therapeutic tion therapy was first used for cure in the principles may be useful for extrapolation early years of the 20th century. Curabil to other tumors. Such unique maracteris ityof the first cancer with drugs is a recent tics as the temnique of dosing and the phenomenon: choriocarcinoma in 1956.

The Pathology of Trophoblastic Tumours

Transplantation Immunity and the Trophoblast
Alternations of the Thymo-Lymphatic System in Malignant Trophoblastic Disease
Serial Passage of Choriocarcinoma of Women in The Hamster Cheek-Pouch
Synopsis of discussion I
Trophoblastic or Chorionic Tumors as Observed in the Philippines
The Natural History of Choriocarcinoma
Early Development of Choriocarcinoma
A Study of Choriocarcinoma. Its Incidence in India and Its Aetiopathogenesis
Observation on Some Aspects of Hydatidiform Mole and Choriocarcinoma in Indonesia
Synopsis of discussion II
The Mechanism of Action of Folic Acid Antagonists
Eight Years Experience with the Chemotherapy of Choriocarcinoma and Related Trophoblastic Tumors in Women
On the Prevention and Treatment of Choriocarcinoma
Chemotherapeutic Prophylaxis Against the Development of Choriocarcinoma Following the Removal of Hydatidiform Mole
An Observation on the Prophylactic Use of Chemotherapy After Termination of Hydatidiform Mole
The Effect of Methotrexate in Trophoblastic Diseases
Methotrexate Treatment in Choriocarcinoma (Preliminary Report)
Synopsis of discussion III
Urinary Excretion of Gonadotropin and the Estrogens in Hydatidiform Mole and Choriocarcinoma
Endocrinological Studies Relating to Trophoblastic Disease in Man
Pelvic Angiography in the Management of Malignant Trophoblastic Disease
Diagnosis of Hydatidiform Mole and Related Trophoblastic Diseases. A Further Study of the Galli-Mainini Bioassay Test
Comments on the Measurement of HCG as a Tumor Specific Substance
Urinary Estrogen Excretion in Chorionic Tumor Patients
Quantitative Human Chorionic Gonadotropin Immunoassay
Synopsis of discussion IV
Chemotherapy of Chorionic Tumors
The Use of 6-Mercaptopurine with Methotrexate in the Treatment of Trophoblastic Tumors
Remissions Induced in Patients with Trophoblastic Tumors by 6-Diazo-5-Oxo-L-Norleucine (DON)
Fundamental Problems of Chemotherapy of Choriocarcinoma
Clinical Effects of Vinblastine in Chorionic Tumors
The Clinical Evalution of Various Anticancer Agents on Chorionic Tumors
Chemotherapeutic and Immunological Considerations on the Response of Choriocarcinomas
Synopsis of discussion V
Integration of Treatment Methods in Trophoblastic Growths
Synopsis of discussion VI
Appendix I
Appendix II
Appendix III.