Springer Handbook of Enzymes provides data on enzymes sufficiently well characterized. It offers concise and complete descriptions of some 5,000 enzymes and their application areas. Data sheets are arranged in their EC-Number sequence and the volumes themselves are arranged according to enzyme classes.

This new, second edition reflects considerable progress in enzymology: many enzymes are newly classified or reclassified. Each entry is correlated with references and one or more source organisms. New datafields are created: application and engineering (for the properties of enzymes where the sequence has been changed). The total amount of material contained in the Handbook has more than doubled so that the complete second edition consists of 39 volumes as well as a Synonym Index. In addition, starting in 2009, all newly classified enzymes are treated in Supplement Volumes.

Springer Handbook of Enzymes is an ideal source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences, as well as for medicinal applications.

?-Butyrobetaine dioxygenase

Procollagen-proline dioxygenase
Pyrimidine-deoxynucleoside 2?-dioxygenase
Procollagen-lysine 5-dioxygenase
5-Hydroxymethyluracil,2-oxoglutarate dioxygenase
Thymine dioxygenase
Procollagen-proline 3-dioxygenase
Trimethyllysine dioxygenase
Naringenin 3-dioxygenase
Pyrimidine-deoxynucleoside 1?-dioxygenase
Hyoscyamine (6S)-dioxygenase
Gibberellin-44 dioxygenase
Gibberellin 2?-dioxygenase
6?-Hydroxyhyoscyamine epoxidase
Gibberellin ?-hydroxylase
Gibberellin ?-dioxygenase
Taurine dioxygenase
Phytanoyl-CoA dioxygenase
Leucocyanidin oxygenase
Desacetoxyvindoline 4-hydroxylase
Clavaminate synthase
Anthranilate 1,2-dioxygenase (deaminating, decarboxylating)
Anthranilate 2,3-dioxygenase (deaminating)
Benzene 1,2-dioxygenase
3-Hydroxy-2-methylpyridinecarboxylate dioxygenase
5-Pyridoxate dioxygenase
2-Hydroxycyclohexanone 2-monooxygenase
Phthalate 4,5-dioxygenase
4-Sulfobenzoate 3,4-dioxygenase
4-Chlorophenylacetate 3,4-dioxygenase
Benzoate 1,2-dioxygenase
Toluene dioxygenase
Naphthalene 1,2-dioxygenase
2-Chlorobenzoate 1,2-dioxygenase
2-Aminobenzenesulfonate 2,3-dioxygenase
Terephthalate 1,2-dioxygenase
2-Hydroxyquinoline 5,6-dioxygenase
Nitric oxide dioxygenase
Biphenyl 2,3-dioxygenase
Salicylate 1-monooxygenase
4-Hydroxybenzoate 3-monooxygenase
4-Hydroxyphenylacetate 3-monooxygenase
Melilotate 3-monooxygenase
Imidazoleacetate 4-monooxygenase
Orcinol 2-monooxygenase
Phenol 2-monooxygenase
Dimethylaniline monooxygenase (N-oxide-forming)
Kynurenine 3-monooxygenase
2,6-Dihydroxypyridine 3-monooxygenase
trans-Cinnamate 4-monooxygenase
Benzoate 4-monooxygenase
Calcidiol 1 -monooxygenase
trans-Cinnamate 2-monooxygenase
Cholestanetriol26-monooxygenase
Cyclopentanone monooxygenase
Cholesterol 7?-monooxygenase
4-Hydroxyphenylacetate 1-monooxygenase
Taxifolin 8-monooxygenase
2,4-Dichlorophenol 6-monooxygenase
Flavonoid 3?-monooxygenase
Cyclohexanone monooxygenase
3-Hydroxybenzoate 4-monooxygenase
3-Hydroxybenzoate 6-monooxygenase
Methane monooxygenase
Phosphatidylcholine 12-monooxygenase
4-Aminobenzoate 1 -monooxygenase
3,9-Dihydroxypterocarpan 6a-monooxygenase
4-Nitrophenol 2-monooxygenase
Leukotriene-B4 20-monooxygenase
2-Nitrophenol 2-monooxygenase
Albendazole monooxygenase
4-Hydroxybenzoate 3-monooxygenase [NAD(P)H]
Leukotriene-E4 20-monooxygenase
Anthranilate 3-monooxygenase (deaminating)
5-O-(4-Coumaroyl)-D-quinate 3?- monooxygenase
Methyltetrahydroprotoberberine 14- monooxygenase
Anhydrotetracycline monooxygenase
Nitric-oxide synthase
Anthraniloyl-CoA monooxygenase
Tyrosine N-monooxygenase
Hydroxyphenylacetonitrile 2-monooxygenase
Questin monooxygenase
2-Hyd roxybiphenyl 3-monooxygenase
CMP-N-Acetylneuraminate monooxygenase
(?)-Menthol monooxygenase
(?)-Limonene 3-monooxygenase
(-)-Limonene 6-monooxygenase
(?)-Limonene 7-monooxygenase
Pentachlorophenol monooxygenase
6-Oxocineole dehydrogenase
Isoflavone 3?-hydroxylase
Isoflavone 2?-hydroxylase
Ketosteroid monooxygenase
Protopine 6-monooxygenase
Dihydrosanguinarine 10-monooxygenase
Dihydrochelirubine 12-monooxygenase
Benzoyl-CoA 3-monooxygenase
l-Lysine 6-monooxygenase (NADPH)
27-Hydroxycholesterol 7?-monooxygenase
2-Hydroxyquinoline 8-monooxygenase
4-Hydroxyquinoline 3-monooxygenase
3-Hydroxyphenylacetate 6-hydroxylase
4-Hydroxybenzoate 1 -hydroxylase
2-Hydroxyquinoline 8-monooxygenase
2-Hydroxycyclohexanone 2-monooxygenase.-Quinine 3-monooxygenase
4-Hydroxyphenylacetaldehyde oxime monooxygenase
Alkene monooxygenase
Sterol 14-demethylase
N-Methylcoclaurine 3?-monooxygenase
Methylsterol monooxygenase
Tabersonine 16-hydroxylase
7-Deoxyloganin 7-hydroxylase
Vinorine hydroxylase
Taxane 10?-hydroxylase
Taxane 13 ?-hydroxylase
ent-Kaurene oxidase
ent-Kaurenoic acid oxidase
(R)-Limonene 6-monooxygenase
Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
Unspecific monooxygenase
Benzopyrene 3-monooxygenase
Alkanal monooxygenase (FMN-linked)
Choline monooxygenase
Alkanesulfonate monooxygenase.