Clinical Research for Surgeons
Clinical Research for Surgeons
Clinical Research for Surgeons is a practical guide for understanding, planning, conducting, and evaluating surgical research. It covers the principles of evidence-based surgery and applies these principles to the design of suitable research studies. The reader will come to fully understand important concepts such as case-control study, prospective cohort study, randomized trial, and reliability study. The book provides valuable discussions of the critical appraisal of published clinical studies, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care.
Highlights:
- Insights from experienced surgeons and veteran researchers- Easy-to-reference text boxes with Key Concepts, Jargon Simplified, and Examples from the Literature- Coverage of both open and minimally-invasive surgical procedures- 50 illustrations demonstrating key points
This book is a valuable reference for clinicians and residents in a range of disciplines, including general surgery, orthopedic surgery, plastic and reconstructive surgery, urology, neurosurgery, otolaryngology-head and neck surgery, interventional radiology, cardiac surgery.
<p><strong>Part I Why We Need Clinical Research</strong><br>1 Historical Perspective of Clinical Research<br>2 Evidence-Based Surgery Defined<br>3 Myths and Misconceptions about Evidence-Based Medicine<br>4 Becoming and Evidence-Based Surgeon<br><strong>Part II Principles of Clinical Research</strong><br>5 Various Research Design Classifications<br>6 Hierarchy of Research Studies: From Case Series to Meta-Analyses<br>7 Randomized and Nonrandomized Studies<br><strong><em>Part IIA Understanding Research Study Design</em></strong><br>8 The Clinical Case Series<br>9 The Case&ndsah;Control Study<br>10 The Prospective Cohort Study<br>11 The Randomized Trial<br>12 Meta-Analyses<br>13 Economic Analysis<br>14 The Diagnostic Study<br>15 The Reliability Study<br><strong><em>Part IIB Understanding Outcomes Measurement</em></strong><br>16 The Classification of Outcomes<br>17 What Makes an Outcome Measure Useful<br>18 Common Generic Outcome Scales for Surgeons<br>19 Common Disease-Specific Outcome Scales for Surgeons<br><strong><em>Part IIC Understanding Treatment Effects</em></strong><br>20 Common Ways to Present Treatment Effects<br>21 The Confidence Interval Defined<br>22 The <em>P</em> Value Defined<br>23 Errors in Hypothesis Testing<br>24 Clinical versus Statistical Significance<br><strong>Part III Practice of Clinical Research</strong><br><strong><em>Part IIIA Planning a Research Study</em></strong><br>25 The Requirements of a Clinical Research Proposal<br>26 The Identification of a Good Research Question<br>27 How to Conduct a Comprehensive Literature Search<br>28 Guide to Planning a Randomized Trial<br>29 Guide to Planning a Nonrandomized Study<br>30 Study Sample Size<br>31 How to Budget for a Research Study<br>32 Research Ethics, Review Boards, and Consent Forms<br>33 Regulatory Issues in the Evaluation of a New Device or Drug<br>34 Strategies in Research Funding<br><strong><em>Part IIIB Conducting a Research Study</em></strong><br>35 The Roles of the Research Team<br>36 The Role of a Central Methods Center<br>37 The Role of a Data Monitoring Committee<br>38 The Need for Separate Adjudication of Outcomes<br>39 Data Management<br>40 Study Case Report Forms<br>41 The Study Manual of Operations<br><strong><em>Part IIIC Practical Guide to Statistical Analysis</em></strong><br>42 Review of Basic Statistical Principles<br>43 Statistical Means and Proportions<br>44 Regression Analysis<br>45 Analysis of Variance<br>46 Correlation Defined</p>
Bhandari, Mohit
Joensson, Anders
| ISBN | 9783131439314 |
|---|---|
| Artikelnummer | 9783131439314 |
| Medientyp | Buch |
| Copyrightjahr | 2008 |
| Verlag | Thieme, Stuttgart |
| Umfang | 350 Seiten |
| Abbildungen | 50 Abb. |
| Sprache | Englisch |
