Clinical Trials in 'Early' Breast Cancer

Methodological and Clinical Aspects of Treatment Comparisons Proceedings of a Symposium, Heidelberg, Germany, 4th to 8th December, 1978

Clinical Trials in 'Early' Breast Cancer

Methodological and Clinical Aspects of Treatment Comparisons Proceedings of a Symposium, Heidelberg, Germany, 4th to 8th December, 1978

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1. General Aspects
Prognostic Factors and Nosological Criteria of Breast Cancer from the Pathologist's Point of View
Growth Rate of Tumours and Natural Life Expectancy
The Reporting of Non-significant Results in Clinical Trials
Notes on Clinical Trial Methodology
2. Design and Performance of Clinical Trials
The Cardiff Mastectomy Trial
Experiences from a Multicentric Trial of Adjuvant Chemotherapy
Thirty Years Experience with Breast Cancer Clinical Trials at the Christie Hospital in Manchester - Clinical Aspects
Thirty Years Experience of Breast Cancer Trials in Manchester - Statistical Aspects
The King's/Cambridge Trial
Operable Breast Cancer with Positive Axillary Nodes: The Experience of the Milan Cancer Institute
3. Treatment Departures
Problems in Withdrawal of Patients in a Randomized Study, when Treatment in One of the Groups Cannot be Carried Out
Treatment Departure and Survival Analysis in a Randomized Trial on the Value of Pre- and Postoperative Radiotherapy in Breast Cancer
4. Stochastic Models
Stochastic Models in Clinical Trials
5. Regression Models
Aspects of the Cox Model in the Analysis of Survival Data
Time Dependend Covariates
A Large Sample Study of the Estimate for the Survival Distribution in Cox's Regression Model
6. Competing Risks
Comparing Treatments, Adjusting for Competing Risks
Why the Present Approach to Competing Risks Should be Abandoned
Competing Risk Models in Early Breast Cancer Trials
7. Log Rank Test
Some Extensions of the Log Rank Test
Discussion
Appendix Controlled Illness Processes with Incomplete Information - A Re-examination of the Basic Hypothesis in Constructing Stochastic Models P. Tautu
List of Participants.
ISBN 9783540095309
Artikelnummer 9783540095309
Medientyp Buch
Auflage Softcover reprint of the original 1st ed. 1979
Copyrightjahr 1979
Verlag Springer, Berlin
Umfang 283 Seiten
Abbildungen VI, 283 p.
Sprache Englisch