1;Foreword to the third edition;6 2;Preface to the third edition;7 3;Acknowledgement;9 4;Contents;10 5;1 Introduction and Fundamentals of Pinhole Scintigraphy;18 5.1;1.1 A History of Nuclear Bone Imaging;21 5.2;1.2 Histology and Physiology of Bone;23 5.3;1.3 Mechanism of Bone Adsorption of 99mTc-Radiopharmaceuticals;24 5.4;1.4 Bone Imaging Radiopharmaceuticals;24 5.5;1.5 Bone Marrow Scan Radiopharmaceuticals;25 5.6;1.6 Fundamentals of Pinhole Scintigraphy;25 5.7;1.7 Rationale and Techniques of Pinhole Scintigraphy;27 5.8;References;30 6;2 Dual-Head Planar Pinhole Scintigraphy and Pinhole SPECT of Bone;32 6.1;2.1 Dual-Head Planar Pinhole Scintigraphy;32 6.2;2.2 Pinhole SPECT of Bone;34 6.3;References;41 7;3 Clinical Applications;42 7.1;3.1 Abnormal Bone Scan;44 7.2;3.2 Altered Biodistribution of Radiopharmaceutical;45 7.3;References;45 8;4 Normal Pinhole Scintigraphic Anatomy of Bone and Joint;46 8.1;4.1 Skull and Face;46 8.2;4.2 Neck;49 8.3;4.3 Thoracic Cage;51 8.4;4.4 Shoulder;52 8.5;4.5 Thoracic and Lumbar Spine;53 8.6;4.6 Sacrum and Sacroiliac Joints;57 8.7;4.7 Pelvis and Hip;58 8.8;4.8 Limbs;62 8.9;References;68 9;5 Normal Variants and Artifacts;69 9.1;5.1 Normal Variants;69 9.2;5.2 Artifacts;83 9.3;References;87 10;6 Infective and Inflammatory Diseases of Bone;89 10.1;6.1 Acute Osteomyelitis;89 10.2;6.2 Subacute and Chronic Osteomyelitis;93 10.3;6.3 Acute and Chronic Infective Osteitis and Cortical Abscess;99 10.4;6.4 Acute Infective Periostitis;102 10.5;6.5 Special Forms of Osteomyelitis;102 10.6;6.6 Tuberculosis of Bone;111 10.7;6.7 111In- and 99mTc-Leukocyte and 67Ga Citrate Scintigraphy in Skeletal Infections;115 10.8;References;118 11;7 Noninfective Osteitides;119 11.1;7.1 Osteitis Condensans Ilii;119 11.2;7.2 Osteitis Pubis;121 11.3;7.3 Condensing Osteitis of the Clavicle;122 11.4;7.4 Sternocostoclavicular Hyperostosis;124 11.5;7.5 Infantile Cortical Hyperostosis ( Caffey's Disease) ;127 11.6;7.6 Osteitis Deformans ( Paget'sDisease of Bone);127 11.7;7.7 Odontogenous Osteitis of the Mandible ( Periapical Abscess);127 11.8;7.8 Radiation Osteitis ( Osteonecrosis);129 11.9;References;131 12;8 Diseases of Joints and Soft- Tissue Infections;132 12.1;8.1 Sterile and Sympathetic Arthritis;134 12.2;8.2 Infective Arthritis;140 12.3;8.3 Soft- Tissue Infections;150 12.4;References;153 13;9 Degenerative Joint Diseases;154 13.1;9.1 Sacroiliac Joint;159 13.2;9.2 Hip;160 13.3;9.3 Knee;161 13.4;9.4 Patella;164 13.5;9.5 Ankle and Tarsal Joints;166 13.6;9.6 Shoulder;168 13.7;9.7 Sternum;171 13.8;9.8 Elbow;172 13.9;9.9 Wrist and Carpal Joints;174 13.10;9.10 Spine;177 13.11;9.11 Other Common Sites of Osteoarthritis;184 13.12;9.12 Generalized Osteoarthritis;186 13.13;9.13 Degeneration-Related Disorders of the Spine;188 13.14;References;196 14;10 Rheumatoid Arthritis;198 14.1;10.1 Hand (Fingers);202 14.2;10.2 Wrist;204 14.3;10.3 Elbow;207 14.4;10.4 Shoulder;208 14.5;10.5 Sternum;211 14.6;10.6 Foot;213 14.7;10.7 Ankle and Tarsus;213 14.8;10.8 Knee;216 14.9;10.9 Hip;218 14.10;10.10 Sacroiliac Joint;220 14.11;10.11 Spine;220 14.12;10.12 Temporomandibular Joint;222 14.13;10.13 Insufficiency Fracture in Rheumatoid Arthritis;225 14.14;10.14 Juvenile Rheumatoid Arthritis;225 14.15;10.15 Nuclear Angiography in Rheumatoid Arthritis;227 14.16;10.16 Molecular Imaging in Rheumatoid Arthritis;228 14.17;10.17 99mTc-FDG PET-CT in Rheumatoid Arthritis;228 14.18;References;230 15;11 Seronegative Spondyloarthropathies;231 15.1;11.1 Ankylosing Spondylitis;232 15.2;11.2 Reiter's Syndrome;237 15.3;11.3 Psoriatic Arthritis;245 15.4;11.4 Enteropathic Arthropathies;248 15.5;References;249 16;12 Other Rheumatic Osteoarthropathies and Soft- Tissue Rheumatism Syndromes;250 16.1;12.1 Sjögren's Syndrome;252 16.2;12.2 Behçet's Syndrome;252 16.3;12.3 Systemic Lupus Erythematosus;256 16.4;12.4 Gouty Arthritis;258 16.5;12.5 Charcot's Joint or Neuroarthropathy;263 16.6;12.6 Secondary Hypertrophic Osteoarthropathy;263 16.7;12.7 Periarticular Soft- Tissue Rheumatism Syndrom