Now including Supplement 1 

Comprehensive Asymmetric Catalysis comprehensively and critically reviews methods for the catalytic preparation of chiral organic compounds. This major reference set presents the state of the art in this area. The internationally acclaimed editors and the contributors, who are recognized experts in the field, guarantee the authoritative and timely coverage. This set is not only the principal reference source for synthetic organic chemists, but also for all scientific researchers who require chiral compounds in their work (for example in biochemical investigations and molecular medicine) as well as for pharmaceutical chemists, agricultural chemists and other industrial researchers who prepare chiral compounds. Since the publication of the first edition 1999 research rapidly went on. These results are summarised in the first supplement which is added to the three volume bookset.

<p> Supplement 1:</p><p>6.1. T. Ohkuma, R. Noyori: Hydrogenation of Carbonyl Groups</p><p>6.2. T. Ohkuma, R. Noyori: Hydrogenation of Imino Groups</p><p>6.3. T. Ohkuma, R. Noyori: Hydrosilylation of Carbonyl and Imino Groups</p><p>14. T. Ohkuma, R. Noyori: Heck Reaction </p><p>26.1. K. Soai, T. Shibata: Alkylation of C=O</p><p>26.2. K. Hatanaka, H. Yamamoto: Alkylation of C=N</p><p>28. P. Vachal, E.N. Jacobsen: Cyanation of Carbonyl and Imino Groups</p><p>29.3. M. Shibasaki, H. Gröger, M. Kanai: Nitroaldol Reaction</p><p>31.2. M. Yamaguchi: Catalytic Conjugate Addition of Stabilized Carbanion </p><p>34.1. D.L. Hughes: Alkylation of Enolates</p><p>39. A.H. Hoveyda, K.E. Murphy: Combinatorial Approaches</p><p>New Chapters</p><p>16.4. H.M.L. Davies: C-H Insertion Reactions, Cycloadditions and Ylide Formation of Diazo Compounds</p><p>29.4. M. Shibasaki, N. Yoshikawa, S. Matsunaga: Direct Catalytic Asymmetric Aldol Reaction</p><p>29.5. S. Kobayashi, M. Ueno: Mannich Reaction</p><p>43. E.R. Jarvo, S.J. Miller: Acylation Reactions</p><p>44. A.H. Hoveyda, R.R. Schrock: Metathesis Reactions</p>Volume I <p>1 Introduction</p><p>Andreas Pfaltz</p><p>2 Historical Perspective</p><p>Henri B. Kagan</p><p>3 Basic Principles of Asymmetric Synthesis</p><p>Johann Mulzer</p><p>4 General Aspects of Asymmetric Catalysis</p><p>4.1 Non-Linear Effects and Autocatalysis</p><p>Henri B. Kagan, T. O. Luukas</p><p>5 Hydrogenation of Carbon-Carbon Double Bonds</p><p>5.1 Hydrogenation of Functionalized Carbon-Carbon Double Bonds</p><p>John M. Brown</p><p>5.2 Hydrogenation of Non-Functionalized Carbon-Carbon Double Bonds</p><p>Ronald L. Halterman</p><p>6 Reduction of Carbonyl and Imino Groups</p><p>6.1 Hydrogenation of Carbonyl Groups</p><p>T. Ohkuma á R. Noyori</p><p>6.2 Hydrogenation of Imino Groups</p><p>Hans-Ulrich Blaser, Felix Spindler</p><p>6.3 Hydrosilylation of Carbonyl and Imino Groups</p><p>Hisao Nishiyama</p><p>6.4 Hydroboration of Carbonyl Groups</p><p>Shinichi Itsuno</p><p>7 Hydrosilylation of Carbon-Carbon Double Bond</p><p>Tamio Hayashi</p><p>8 Hydroalumination of Carbon-Carbon Double Bonds</p><p>Mark Lautens, Tomislav Rovis</p><p>9 Hydroboration of Carbon-Carbon Double Bonds</p><p>Tamio Hayashi</p><p>10 Hydrocyanation of Carbon-Carbon Double Bonds</p><p>T.V. RajanBabu, Albert L. Casalnuovo</p><p>11 Hydrocarbonylation of Carbon-Carbon Double Bonds</p><p>Kyoko Nozaki</p><p>12 Hydrovinylation of Carbon-Carbon Double Bonds</p><p>T.V. RajanBabu</p><p>13 Carbometalation of Carbon-Carbon Double Bonds</p><p>Amir H. Hoveyda, Nicola M. Heron</p><p>14 Heck Reaction</p><p>Masakatsu Shibasaki, Erasmus M. Vogl</p><p>Volume II</p><p>15 Pauson-Khand Type Reactions</p><p>Stephen L. Buchwald, Frederick A. Hicks</p><p>16 Cyclopropanation and C-H Insertion Reactions</p><p>16.1 Cyclopropanation and C-H Insertion with Cu</p><p>Andreas Pfaltz</p><p>16.2 Cyc</p>