Concise Manual of Hematology and Oncology
E-Book
Concise Manual of Hematology and Oncology
The Concise Manual of Hematology and Oncology is a practice-oriented manual of medical oncology and hematology for day-to-day use in caring for patients hematologic and neoplastic diseases. It is founded on the longstanding experience of a large specialized university department accustomed to having to provide reliable advice in a broad range of circumstances. We have deliberately chosen not to give a comprehensive review of the various subjects but have instead focused on practical methods which have proven to be useful in our experience, with special emphasis on standardizing chemotherapy protocols.
1;Preface;4<br />2;Contents;5<br />3;1 Principles of Medical Oncology;18<br />3.1;1.1 Epidemiology;18<br />3.2;1.2 Carcinogenesis, Molecular Tumor Biology;20<br />3.3;1.3 Hematopoiesis and Development of Hematological Neoplasia;24<br />3.4;1.4 Prevention and Screening;27<br />3.5;1.5 Classification of Diseases and ICD System;31<br />3.6;1.6 Tumor Classification and TNM System;34<br />3.7;1.7 Indications for Tumor Therapy;36<br />3.8;1.8 Performance Status of Tumor Patients ( Performance Status Scales );38<br />3.9;1.9 Response Evaluation in Solid Tumors;39<br />3.10;1.10 Common Toxicity Criteria ( NCI);42<br />3.11;1.11 Assessing the Quality of Life of Tumor Patients;47<br />3.12;1.12 Evidence- based Medicine ( EBM), Guidelines and Quality Management;49<br />3.13;1.13 Electronic Media;52<br />4;2 Special Diagnostics;56<br />4.1;2.1 Cytogenetics and Fluorescence In Situ Hybridization ( FISH);56<br />4.2;2.2 Molecular Diagnosis;59<br />4.3;2.3 Gene Expression Analysis using Microarrays;62<br />4.4;2.4 Tumor Markers;64<br />4.5;2.5 CD Antigens and Immunocytological Diagnosis;68<br />4.6;2.6 HLA System and MHC;79<br />5;3 Pharmacology and Pharmacotherapy;82<br />5.1;3.1 Basic Principles of Chemotherapy;82<br />5.2;3.2 Cytostatic Drugs;86<br />5.2.1;3.2.1 Characteristics of Clinically Used Cytostatic Drugs;88<br />5.2.2;3.2.2 Check List Cytostatic Treatment;148<br />5.2.3;3.2.3 Drug Dosage Calculation Based on Body Surface Area ( BSA);149<br />5.2.4;3.2.4 Dose Adjustment of Cytostatic Drugs;151<br />5.2.5;3.2.5 Chemotherapy During Pregnancy and Lactation;158<br />5.2.6;3.2.6 Selected Cytostatic Drug Incompatibilities;160<br />5.2.7;3.2.7 Preparation and Stability of Cytostatics;163<br />5.3;3.3 Hormone Therapy;170<br />5.3.1;3.3.1 Characterization of Hormone Treatments in Oncology;173<br />5.4;3.4 Cytokines;187<br />5.5;3.5 Monoclonal Antibodies;195<br />5.6;3.6 Specific Protein Kinase Inhibitors ( Targeted Therapies );205<br />5.7;3.7 Drug Development and Clinical Studies;215<br />5.8;3.8 Pharmacogenetics and Pharmacogenomics;218<br />6;4 Supportive Treatment;221<br />6.1;4.1 Antiemetic Prophylaxis and Therapy;221<br />6.2;4.2 Antibiotic Treatment and Neutropenic Fever;228<br />6.3;4.3 Growth Factors;235<br />6.4;4.4 Nutrition in Cancer Patients;242<br />6.5;4.5 Pain Control;252<br />6.6;4.6 Fatigue;258<br />6.7;4.7 Bisphosphonates;260<br />6.8;4.8 Malignant Effusions;266<br />6.8.1;4.8.1 Malignant Pleural Effusion;267<br />6.8.2;4.8.2 Malignant Pericardial Effusion;271<br />6.8.3;4.8.3 Malignant Ascites;274<br />6.9;4.9 Transfusion Therapy;278<br />6.10;4.10 Human Sperm Cryopreservation;288<br />6.11;4.11 Cryopreservation of Human Pronuclear Oocytes;291<br />6.12;4.12 Sexual Dysfunction;293<br />6.13;4.13 Physiotherapy and Sports Medicine;295<br />6.14;4.14 Principles of Oncology Nursing Care;298<br />6.15;4.15 Psycho- oncological Care;303<br />6.16;4.16 Rehabilitation;306<br />7;5 Particular Treatment Procedures;310<br />7.1;5.1 Hematopoetic Stem Cell Technology ( Harvesting, Culture, Purging);310<br />7.2;5.2 Autologous Hematopoetic Stem Cell Transplantation;313<br />7.3;5.3 Allogeneic Hematopoetic Stem Cell Transplantation;319<br />7.4;5.4 Granulocyte Transfusion;326<br />7.5;5.5 Immunotherapy;328<br />7.6;5.6 Gene Therapy;332<br />7.7;5.7 Inhibition of Angiogenesis;336<br />7.8;5.8 Developmental Therapeutics;339<br />8;6 Hematology and Hemostasis;344<br />8.1;6.1 Aplastic Anemia;344<br />8.2;6.2 Neutropenia and Agranulocytosis;349<br />8.3;6.3 Thrombocytopenia;353<br />8.3.1;6.3.1 Immune ( Idiopathic) Thrombocytopenic Purpura ( ITP, Werlhof s Disease);356<br />8.3.2;6.3.2 Heparin- induced Thrombocytopenia ( HIT);360<br />8.3.3;6.3.3 Thrombotic Microangiopathies ( TTP- HUS);362<br />8.4;6.4 Anemia;365<br />8.4.1;6.4.1 Hypochromic Anemia;368<br />8.4.2;6.4.2 Megaloblastic Anemia;372<br />8.4.3;6.4.3 Hemolytic Anemia;376<br />8.4.4;6.4.4 Normochromic Anemia;386<br />8.5;6.5 Coagulation Disorders;388<br />8.5.1;6.5.1 Acquired Coagulation Disorders;393<br />8.5.2;6.5.2 Factor VIII Deficiency ( Hemophilia A);398<br />8.5.3;6.5.3 Factor IX Deficiency ( Hemophilia B);401<br />8.5.4;6.5.4 Von Willebrand s Disease ( VWD);403<br />8.5.5;6.5.5 Disseminated Intravascular Coagulation ( DIC);406<br />8.6;6.6 Thromboembolism and Thrombophilia;410<br />9;7 Hematological Neoplasia;417<br />9.
Berger, Dietmar P.
Engelhardt, Monika
Henß, Hartmut
| ISBN | 9783540732778 |
|---|---|
| Artikelnummer | 9783540732778 |
| Medientyp | E-Book - PDF |
| Copyrightjahr | 2008 |
| Verlag | Springer-Verlag |
| Umfang | 1002 Seiten |
| Sprache | Englisch |
| Kopierschutz | Digitales Wasserzeichen |
