This updated second edition covers the molecular biology, genome engineering tools and comprehensive analysis techniques for Corynebacterium glutamicum. Aside from modern omics-based approaches, the authors also focus on cell physiology, including cell division, central carbon metabolic pathways, and the respiratory chain. Readers will learn how primary mechanisms like energy metabolism can be applied in processes like biorefinery. Newly added topics include cell envelope structures and aromatic compound metabolism in C. glutamicum. These chapters will be particularly useful for those interested in the microbial production of commodity chemicals, fuels, and proteins.

Corynebacteriacea are already some of the most important industrial microorganisms. Understanding the cell physiology of C. glutamicum will help manufacturers to increase their product range and productivity through efficient metabolic engineering.

Part I. Characteristics of Corynebacterium glutamicum

Chromosome Organization and Cell Growth of Corynebacterium glutamicum
Architecture and Biogenesis of the Cell Envelope of Corynebacterium glutamicum
Respiratory Chain and Energy Metabolism of Corynebacterium glutamicum
Part II. Regulation at Various Levels
Sigma Factors of RNA Polymerase in Corynebacterium glutamicum
Global Transcriptional Regulators Involved in Carbon, Nitrogen, Phosphorus, and Sulfur Metabolisms in Corynebacterium glutamicum
Post-Translational Modifications in Corynebacterium glutamicum
Part III. Amino Acids
Recent Advances in Amino Acid Production
Pathways at Work: Metabolic Flux Analysis of the Industrial Cell Factory Corynebacterium glutamicum
Amino Acid Exporters in Corynebacterium glutamicum
Part IV. Metabolic Design for a Wide Variety of Products
Metabolic Engineering in Corynebacterium glutamicum
Aromatic Compound Catabolism in Corynebacterium glutamicum
Aromatic Compound Production by Corynebacterium glutamicum.