This book represents an invaluable resource for professionals for the diagnosis and treatment of acute kidney injury (AKI) in children and how to select and deliver the appropriate form of renal replacement therapy (RRT). Experts from all over the globe have come together to share their wide experience in the field of Critical Care Nephrology in children. 

Paediatric critical care nephrology is a complex and highly specialised field, presenting challenges and management strategies that are often quite distinct from those seen in adult practice. Therefore,  it is high time to address all the topics in the field of critical care nephrology in children in a unique book which is the first of its kind. This book covers the basics as well as advances in the field of Critical Care Nephrology. Each chapter is dedicated to practical aspects of a particular topic elucidating various management decision points. Each chapter is alsoaccompanied with algorithms, figures and protocols in tabulated format. Information on how to manage specific conditions are contextualized with relevant background anatomy, physiology and biochemistry and practical examples. At the end of the chapter, there are key learning points. 

Paediatricians, nephrologists and paediatric intensivists, as well as paediatric critical care and nephrology nurses in all countries will find this book an invaluable reference text.

<p>Foreword

Preface
Part I. Acute Kidney Injury
Evolution of Acute Kidney Injury in the last 2 decades
Renal function monitoring in a critically sick patient
Acute Kidney Injury-Definitions and Epidemiology
Biomarkers in AKI.- Neonatal AKI including new devices
Sepsis Associated AKI
Acute Kidney Injury in a child after cardiopulmonary
Bypass, post cardiac surgery and Cardio-renal Syndromes
Acute Kidney Injury in stem cell transplant recipients.- Hemolytic Uremic Syndrome
Acute Kidney Injury in liver disease
Renal emergencies in PICU - electrolyte, acid base and blood pressure issues 
Nutrition in a child with Acute Kidney Injury and on CRRT
Outcomes and Renal Recovery
Part II. Renal Replacement Therpay
Continuous Renal Replacement Therapy - Technology and Basic concepts
Timing of initiation of CRRT
Management considerations for the delivery of CRRT in children
Anticoagulation in CRRT
Haemodialysis
Sustained Low Efficiency Dialysis (SLED) and hybrid therapies - Principles and Management
Peritoneal Dialysis
Plasmapheresis and Total plasma exchange in the PICU
Tandem Therapies in Extracorporeal support
Pharmacology of drugs in critically ill patient with AKI and renal replacement therapy
CRRT nursing programme Development
 Future of Paediatric AKI and CRRT
Part III. CRRT in Specific Disease States
CRRT in a child in cardiac ICU
CRRT in a child with sepsis and multi-organ failure
Hyperammonaemia and Inborn Errors of metabolism (IEM)
CRRT in Exogenous Intoxications 
CRRT in Liver Failure and other liver assist devices.</p><p></p>