DNA Methylation: Development, Genetic Disease and Cancer

DNA Methylation: Development, Genetic Disease and Cancer

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in Vorbereitung

It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type to cell type. These patterns can be instrumental in determining cell type and function. Thus, it is not surprising that studies on the role of DNA methylation now occupy center stage in many fields of biology and medicine such as developmental biology, genetic imprinting, genetic disease, tumor biology, gene therapy, cloning of organisms and others. Once again, basic research in molecular biology has provided the essential foundation for investigations of biomedical problems.



The Regulation of Chromatin and DNA-Methylation Patterns in Blood Cell Development
Methylation Dynamics in the Early Mammalian Embryo: Implications of Genome Reprogramming Defects for Development
Epigenetic Regulation in Drosophila
Epimutations in Human Disease
Epigenotypes of Latent Herpesvirus Genomes
Epigenetics of Complex Diseases: From General Theory to Laboratory Experiments
MSL Proteins and the Regulation of Gene Expression
DNA Methylation Profiles of Female Steroid Hormone-Driven Human Malignancies
Genome-wide Analysis of DNA Methylation Changes in Human Malignancies
Decreased Fidelity in Replicating DNA Methylation Patterns in Cancer Cells Leads to Dense Methylation of a CpG Island
Methylation of Endogenous Human Retroelements in Health and Disease
Cancer-Linked DNA Hypomethylation and Its Relationship to Hypermethylation.
ISBN 978-3-642-06830-0
Artikelnummer 9783642068300
Medientyp Buch
Auflage Softcover reprint of hardcover 1st ed. 2006
Copyrightjahr 2010
Verlag Springer, Berlin
Umfang IX, 284 Seiten
Abbildungen IX, 284 p.
Sprache Englisch