DNA and RNA Nanobiotechnologies in Medicine: Diagnosis and Treatment of Diseases

DNA and RNA Nanobiotechnologies in Medicine: Diagnosis and Treatment of Diseases

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in Vorbereitung

This book will provide latest insights in the functional potentials of ribonucleic acids in medine and the use of Spiegelmer and Spiegelzyme systems. It will also deal with a new type of delivery systems for cellular targeting.

Introduction
RNA Nanotechnology: methods for synthesis, conjugation, assembly and application of RNA nanoparticles
Adsorption of double-stranded DNA to graphene oxide preventing enzymatic digestion
Electrogenerated chemiluminescence of conjugated polymer films from patterned electrodes
Use of RNA structure flexibility data in nanostructure modeling
Informatic resources for identifying and annotating structural RNA motifs
A nanostructure made of a bacterial noncoding RNA
HAPIscreen, a method for high-throughput aptamer identification
Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in DNA
Bifacial nucleoside as a surrogate for both T and A in duplex DNA
Functionally important structural elements of U12 snRNA
Self-assembling RNA nanorings based on RNAI/II inverse kissing complexes
Automatic molecular weaving prototyped by using single-stranded DNA
Nucleic Acid Aptamers: Clinical Applications and Promising New Horizons
Nanotextured Substrates With Immobilized Aptamers for Cancer Cell Isolation and Cytology
Targeting cancer with peptide aptamers
Synthetic, biofunctional nucleic acid-based molecular devices
Inducible site-selective bottom-up assembly of virus-derived nanotube arrays on RNA-equipped wafers
Special delivery: targeted therapy with small RNAs, RNAi nanomedicines: challenges and opportunities within the immune system
Pyrene-functionalized oligonucleotides and locked nucleic acids (LNAs): Tools for fundamental research, diagnostics, and nanotechnology
Stabilizing RNA by the sonochemical formation of RNA nanospheres. Sonochemical synthesis of DNA nanospheres
Nucleic acid based molecular devices
Nanoparticle therapeutics: FDA approval, clinical trials, regulatory pathways, and case study
A sol-gel-based microfluidics system enhances the efficiency of RNA aptamer selection
Hierarchical nanotextured microelectrodes overcome the molecular transport barrier to achieve rapid, direct bacterial detection
Recent developments in lipid-based pharmaceutical nanocarriers
Targeted delivery of RNAi therapeutics for cancer therapy
DNAsomes: Multifunctional DNA-based nanocarriers
Reversible and Controllable Nanolocomotion of an RNA-Processing Machinery
Scavenger receptors mediate cellular uptake of polyvalent oligonucleotide-functionalized gold nanoparticles
A highly sensitive microRNA biosensor based on ruthenium oxide nanoparticle-initiated polymerization of aniline
Preparation and high-resolution microscopy of gold cluster labeled nucleic acid conjugates and nanodevices
Kinetically grafting G-quadruplexes onto DNA nanostructures for structure and function encoding via a DNA machine
Synthesis of glycerol nucleic acid (GNA) phosphoramidite monomers and oligonucleotide polymers
Cancer immunotherapy and nanomedicine
RNA nanotechnology: inspired by DNA
From nanotechnology to nanomedicine: applications to cancer research
Comparative structural and functional studies of nanoparticle formulations for DNA and siRNA delivery
Advances in novel drug delivery strategies for breast cancer therapy
DNA origami: a history and current perspective
Nanoparticles: a promising modality in the treatment of sarcomas
Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication
Recent developments in oligonucleotide conjugation
In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers
DNA and carbon nanotubes as medicine
LHRH-targeted nanoparticles for cancer therapeutics
Nanoparticle-aptamer conjugates for cancer cell targeting and detection
Evaluation of targets for ovarian cancer gene silencing therapy: in vitro and in vivo approaches
Prediction and design of DNA and RNA structures
siRNA applications in nanomedicine.
ISBN 978-3-642-44352-7
Artikelnummer 9783642443527
Medientyp Buch
Auflage 2013
Copyrightjahr 2015
Verlag Springer, Berlin
Umfang VIII, 460 Seiten
Abbildungen VIII, 460 p. 230 illus., 124 illus. in color.
Sprache Englisch