Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. Evolution has been characterised by a dramatic increase in an organism's body size, which is not only limited to the size of the brain.

Evolutionary Trends in Body Size

Sexual Dimorphism in the Growth of Homo sapiens: Facts, Inferences and Speculation
Genetic Control of Size at Birth
The GH/IGF-1 Axis: Insights from Animal Models
Downstream Mechanisms of Growth Hormone Action
Growth Hormone Receptor Signaling and Differential Actions in Target Tissues Compared to IGF-I
IGF-I and Brain Growth: Multifarious Effects on Developing Neural Cells and Mechanisms of Action
IGF-I Deficiency: Lessons from Human Mutations
Putting IGF-I Biology into a Clinical Perspective
IGF Resistance: The Role of the Type 1 IGF Receptor
The Importance of the National Cooperative Growth Study (NCGS)
Why we are Treating Children with Growth Hormone: Lessons from the French Registry.