1;Preface;5 2;Contents;6 3;Contributors;11 4;Anatomy of the Pancreas;21 4.1;Development of the Pancreas and Response to Disease;22 4.2;Congenital Anomalies of the Pancreas and the Extrahepatic Bile Ducts;28 4.3;Surgical Vascular Anatomy and Histology;37 5;Physiology and Pathophysiology of the Pancreatic Functions;47 5.1;Pancreatic Exocrine Secretion;48 5.2;Physiology and Patho-physiology of Endocrine Pancreatic Secretion;53 5.3;Sphincter of Oddi Physiology and Pathophysiology;65 6;Clinical Standards of Diagnostic Measures;75 6.1;Ultrasound;76 6.2;Contrast-Enhanced CT and MRI;82 6.3;Endoscopic Retrograde Cholangiopancreatography;90 6.4;Fine-Needle Aspiration Biopsy of the Pancreas;100 6.5;FDG-PET and PET/CT in Pancreatic Cancer;111 6.6;Laboratory Diagnosis of Exocrine and Endocrine Dysfunctions in Inflammatoryand Neoplastic Lesions;120 6.7;Guidelines, Clinical Evaluation, Short Track;132 7;Acute Pancreatitis;142 7.1;Etiology and Epidemiology of Acute Pancreatitis;144 7.2;Pathogenesis and Pathophysiology of Acute Pancreatitis;166 7.3;Natural Course of Acute Pancreatitis;176 7.4;Classification of Severe Acute Pancreatitis;186 7.5;Biochemical Diagnosis, Staging, and Prediction;193 7.6;Imaging Diagnosis of Acute Pancreatitis;205 7.7;Nonsurgical Management of Acute Pancreatitis;215 7.8;Indications for the Surgical Management of Necrotizing Pancreatitis;223 7.9;Debridement and Closed Packing for the Treatment of Necrotizing Pancreatitis;230 7.10;Necrosectomy and Redressing;236 7.11;Necrosectomy and Closed Lavage;242 7.12;Infected Necrosis - Minimally Invasive Necrosectomy;252 7.13;Benefits and Limitations of Necrosectomy;260 7.14;Surgical Management of Pancreatic Abscess;264 7.15;Surgical Management of Pseudocysts after Acute Pancreatitis;270 7.16;Interventional Management of Pancreatic Fluid Collections and Abscesses;282 7.17;Pancreatic and Intestinal Fistulas;291 7.18;Late Outcome after Necrosectomy;299 8;Chronic Pancreatitis;303 8.1;Mechanisms of Pain in Chronic Pancreatitis;305 8.2;Natural Course of Chronic Pancreatitis;310 8.3;Chronic Pancreatitis:Inflammatory Mass in the Headof the Pancreas - Pacemakerof Chronic Pancreatitis;319 8.4;Diagnosis: Functional Testing, Radiological Work-up of Chronic Pancreatitis;326 8.5;Medical Management of Chronic Pancreatitis;338 8.6;Tropical Chronic Pancreatitis;355 8.7;Hereditary Chronic Pancreatitis: Diagnosis and Management;366 8.8;Endoscopic Interventional Treatment;377 8.9;Pancreatic Duct Drainage Procedures;389 8.10;Duodenum-Preserving Pancreatic Head Resection;401 8.11;Pancreaticoduodenctomy for Chronic Pancreatitis- With or Without Pylorus Preservation;415 8.12;Central Pancreatectomy;426 8.13;Distal Pancreatectomy in Patients with Chronic Pancreatitis;442 8.14;Total Pancreatectomy;453 8.15;Surgical Treatment of Pseudocysts in Chronic Pancreatitis;458 8.16;Late Outcome After Medical and Surgical Treatment of Chronic Pancreatitis;475 9;Pancreatic Cancer;485 9.1;Epidemiology of Pancreatic Cancer;487 9.2;Pathology of Pancreatic Cancer;495 9.3;Genetic Pathways in Pancreatic Tumorigenesis;510 9.4;The Clinical Assessment of Pancreatic Cancer;524 9.5;The Staging of Pancreatic Cancer;538 9.6;Oncological Management of Pancreatic Cancer in Advanced Stages;546 9.7;Indications for Resection of Pancreatic Cancer;555 9.8;The Kausch-Whipple Pancreatectomy;562 9.9;Pylorus-Preserving Pancreaticoduodenectomy;575 9.10;Management of TumorInvasion/Adhesion to the Superior Mesenteric-Portal Vein During Pancreatectomy;586 9.11;Subtotal Left Resection for Pancreatic Cancer;616 9.12;Total Pancreatectomy for Pancreatic Cancer;630 9.13;Laparoscopic Management of Pancreatic Neoplasms;643 9.14;Bypass Procedures in the Treatment of Nonresectable Carcinoma of the Head of the Pancreas;655 9.15;Resected Pancreatic Cancer;665 9.16;Management of Locally Advanced and Recurrent Pancreas Cancer;678 9.17;Survival After Medical and Surgical Treatment of Pancreatic Adenocarcinoma;684 10;Endocrine Tumors of the Pancreas;694 10.1;