The book provides an updated overview of molecular analysis of human tissues, and the impact this analysis has on diagnosis and prognosis of human diseases. Special emphasis is placed on human cancer and the future directions of the field. Methods of handling clinical tissue samples, including the impact of handling on subsequent molecular analysis, are also discussed. In addition, detailed protocols for molecular analysis of DNA, RNA and protein, with special emphasis on molecular analysis of highly complex human tissue samples containing mixtures of cell populations, are provided.

Clinkal Issues and Tissue Processing

Molecular Pathology Laboratory of the Future
Clinical Utilities of Microdissected Samples
Tissue Processing
Sample Management and Tracking
Methods of Tissue Microanalysis
Tissue Microarrays
Molecular Analysis of Microdissected Samples
Methods of Microdissection and New Technologies
Standard Diagnostic Techniques
DNA Applications
mRNA Applications
Proteomic Applications
Protocols for Tissue Handling and Molecular Analysis.